Ciliary ectosomes: transmissions from the cell's antenna

CR Wood, JL Rosenbaum - Trends in cell biology, 2015 - cell.com
The cilium is the site of function for a variety of membrane receptors, enzymes and signal
transduction modules crucial for a spectrum of cellular processes. Through targeted …

Coevolution of radial glial cells and the cerebral cortex

C De Juan Romero, V Borrell - Glia, 2015 - Wiley Online Library
Radial glia cells play fundamental roles in the development of the cerebral cortex, acting
both as the primary stem and progenitor cells, as well as the guides for neuronal migration …

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

MB Johnson, PP Wang, KD Atabay, EA Murphy… - Nature …, 2015 - nature.com
The human cerebral cortex depends for its normal development and size on a precisely
controlled balance between self-renewal and differentiation of diverse neural progenitor …

Identification of a distinct population of CD133+CXCR4+ cancer stem cells in ovarian cancer

M Cioffi, C D'Alterio, R Camerlingo, V Tirino… - Scientific reports, 2015 - nature.com
CD133 and CXCR4 were evaluated in the NCI-60 cell lines to identify cancer stem cell rich
populations. Screening revealed that, ovarian OVCAR-3,-4 and-5 and colon cancer HT-29 …

Neurogenin 3 expressing cells in the human exocrine pancreas have the capacity for endocrine cell fate

DL Gomez, M O'Driscoll, TP Sheets, RH Hruban… - PloS one, 2015 - journals.plos.org
Neurogenin 3 (NGN3) is necessary and sufficient for endocrine differentiation during
pancreatic development and is expressed by a population of progenitor cells that give rise …

[HTML][HTML] Genetic background and light-dependent progression of photoreceptor cell degeneration in Prominin-1 knockout mice

M Dellett, N Sasai, K Nishide, S Becker… - … & visual science, 2015 - jov.arvojournals.org
Purpose.: Mutations in the Prominin-1 (Prom1) gene are known to cause retinitis pigmentosa
and Stargardt disease, both of which are associated with progressive photoreceptor cell …

Progenitor genealogy in the developing cerebral cortex

S Laguesse, E Peyre, L Nguyen - Cell and tissue research, 2015 - Springer
The mammalian cerebral cortex is characterized by a complex histological organization that
reflects the spatio-temporal stratifications of related stem and neural progenitor cells, which …

CD133+CD44+ Cells Mediate in the Lung Metastasis of Osteosarcoma

A He, X Yang, Y Huang, T Feng, Y Wang… - Journal of cellular …, 2015 - Wiley Online Library
ABSTRACT CD133 and CD44 are commonly used markers of cancer stem cells (CSCs),
which are characterized by their ability for self‐renewal and tumorigenicity. However, the …

Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics

PK Selbo, M Bostad, CE Olsen, VT Edwards… - Photochemical & …, 2015 - pubs.rsc.org
Despite progress in radio-, chemo-and photodynamic-therapy (PDT) of cancer, treatment
resistance still remains a major problem for patients with aggressive tumours. Cancer stem …

[HTML][HTML] An intronic deletion in the PROM1 gene leads to autosomal recessive cone-rod dystrophy

O Eidinger, R Leibu, H Newman, L Rizel… - Molecular …, 2015 - ncbi.nlm.nih.gov
Purpose To investigate the genetic basis for autosomal recessive cone-rod dystrophy (CRD)
in a consanguineous Israeli Jewish family. Methods Patients underwent a detailed …