• More data are available showing that high-quality CPR improves survival from cardiac
arrest, including–Ensuring chest compressions of adequate rate–Ensuring chest …

This review outlines the most frequently used rodent stroke models and discusses their
strengths and shortcomings. Mimicking all aspects of human stroke in one animal model is …

This executive summary provides the essential treatment algorithms for the resuscitation of
children and adults and highlights the main guideline changes since 2010. Detailed …

Background The potential benefit of dual antiplatelet therapy beyond 1 year after a
myocardial infarction has not been established. We investigated the efficacy and safety of …

Background It is uncertain whether bridging anticoagulation is necessary for patients with
atrial fibrillation who need an interruption in warfarin treatment for an elective operation or …

Importance The prevalence of cardiometabolic multimorbidity is increasing. Objective To
estimate reductions in life expectancy associated with cardiometabolic multimorbidity …

An array of highly sensitive pressure sensors entirely made of biodegradable materials is
presented, designed as a single-use flexible patch for application in cardiovascular …

Importance Acute ischemic stroke is a major cause of mortality and morbidity in the United
States. We review the latest data and evidence supporting catheter-directed treatment for …

Importance Uncertainty remains about the efficacy of folic acid therapy for the primary
prevention of stroke because of limited and inconsistent data. Objective To test the primary …

Background Four direct oral anticoagulants (DOACs) have been brought to market for the
treatment of nonvalvular atrial fibrillation and venous thromboembolism. Many forces …