[HTML][HTML] In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment

M Fantini, M Benvenuto, L Masuelli, GV Frajese… - International journal of …, 2015 - mdpi.com
Carcinogenesis is a multistep process triggered by genetic alterations that activate different
signal transduction pathways and cause the progressive transformation of a normal cell into …

Pharmacological studies of artichoke leaf extract and their health benefits

MB Salem, H Affes, K Ksouda, R Dhouibi… - Plant foods for human …, 2015 - Springer
Artichoke (Cynara scolymus) leaf extract was one of the few herbal remedies which the
clinical and experimental trials have complemented each other. Both experimental and …

Effects of initiating moderate alcohol intake on cardiometabolic risk in adults with type 2 diabetes: a 2-year randomized, controlled trial

Y Gepner, R Golan, I Harman-Boehm… - Annals of internal …, 2015 - acpjournals.org
Background: Recommendations for moderate alcohol consumption remain controversial,
particularly in type 2 diabetes mellitus (T2DM). Long-term randomized, controlled trials …

The relationship between phenolic compounds from diet and microbiota: impact on human health

L Valdés, A Cuervo, N Salazar, P Ruas-Madiedo… - Food & function, 2015 - pubs.rsc.org
The human intestinal tract is home to a complex microbial community called microbiota. This
gut microbiota, whilst playing essential roles in the maintenance of the health of the host, is …

The mechanisms of action of flavonoids in the brain: Direct versus indirect effects

C Rendeiro, JS Rhodes, JPE Spencer - Neurochemistry international, 2015 - Elsevier
The projected increase in the incidence of dementia in the population highlights the urgent
need for a more comprehensive understanding of how different aspects of lifestyle, in …

[HTML][HTML] Ferulic acid alleviates changes in a rat model of metabolic syndrome induced by high-carbohydrate, high-fat diet

K Senaphan, U Kukongviriyapan, W Sangartit… - Nutrients, 2015 - mdpi.com
Metabolic syndrome is a cluster of metabolic abnormalities characterized by obesity, insulin
resistance, hypertension and dyslipidemia. Ferulic acid (FA) is the major phenolic …

[PDF][PDF] Chemistry and antioxidant activity of plants containing some phenolic compounds

M Asif - Chemistry international, 2015 - academia.edu
Plant species still serve as a rich source of many novel biologically active compounds. The
interest in phytomedicine and many medicinal plant species are being screened for …

Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan‐3‐ols: A randomized cross‐over study in humans

S Wiese, T Esatbeyoglu, P Winterhalter… - Molecular Nutrition & …, 2015 - Wiley Online Library
Scope Flavan‐3‐ols are abundant polyphenols in human nutrition and are associated with
beneficial health effects. The aim of this study was to comparatively investigate the metabolic …

Polyphenols inhibit hepatitis C virus entry by a new mechanism of action

N Calland, ME Sahuc, S Belouzard, V Pène… - Journal of …, 2015 - Am Soc Microbiol
Despite the validation of direct-acting antivirals for hepatitis C treatment, the discovery of
new compounds with different modes of action may still be of importance for the treatment of …

Bactericidal activity and mechanism of photoirradiated polyphenols against gram-positive and-negative bacteria

K Nakamura, K Ishiyama, H Sheng, H Ikai… - Journal of agricultural …, 2015 - ACS Publications
The bactericidal effect of various types of photoirradiated polyphenols against Gram-positive
and-negative bacteria was evaluated in relation to the mode of action. Gram-positive …