MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension

L Deng, FJ Blanco, H Stevens, R Lu… - Circulation …, 2015 - Am Heart Assoc
Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) remains unclear. The
4 microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered …

Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones

AL Frump, KN Goss, A Vayl… - … of Physiology-Lung …, 2015 - journals.physiology.org
Estrogens are disease modifiers in PAH. Even though female patients exhibit better right
ventricular (RV) function than men, estrogen effects on RV function (a major determinant of …

Increased α1-adrenoreceptor activity is required to sustain blood pressure in female rats under food restriction

AA de Souza, RC de Menezes, AR Abreu, GR Araujo… - Life sciences, 2015 - Elsevier
Aims We evaluated the effect of food restriction (FR) on the various reflexes involved in short
term cardiovascular regulation; we also evaluated the contribution of the sympathetic …

Connexin-mediated regulation of the pulmonary vasculature

Y Dempsie, P Martin, PD Upton - Biochemical Society …, 2015 - portlandpress.com
Pulmonary arterial hypertension (PAH) is a complex, multi-factorial disorder characterized
by both constriction and remodelling of the distal pulmonary vasculature. This leads to …

[HTML][HTML] The imitation game in pulmonary arterial hypertension. Sex, bone morphogenetic protein receptor, and the estrogen paradox

S Singla, RF Machado - … Journal of Respiratory and Critical Care …, 2015 - atsjournals.org
Bone morphogenetic protein receptor type 2 (BMPR2) mutations account for approximately
75% of hereditary pulmonary arterial hypertension (HPAH) cases and 25% of sporadic …

[PDF][PDF] miR-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension

L Deng, FJ Blanco, HSR Lu, A Caudrillier, M McBride… - academia.edu
Rationale: The pathogenesis of PAH remains unclear. The four microRNAs representing the
miR-143 and miR-145 stem loops are genomically clustered. Objective: To elucidate the …

[HTML][HTML] Sex Differences in the Respiratory System: Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects …

AL Frump, KN Goss, A Vayl, M Albrecht… - American Journal of …, 2015 - ncbi.nlm.nih.gov
Estrogens are disease modifiers in PAH. Even though female patients exhibit better right
ventricular (RV) function than men, estrogen effects on RV function (a major determinant of …

Efeitos da ovariectomia no estresse oxidativo em pulmão e ventrículo direito de ratas com hipertensão arterial pulmonar induzida por monocrotalina

R Siqueira - 2015 - lume.ufrgs.br
Neste estudo foi utilizado o modelo de hipertensão arterial pulmonar (HAP) induzida por
monocrotalina (MCT), que mimetiza esta doença grave e progressiva, a qual tem início com …

Development of liquid chromatography mass spectrometry methods for the monitoring of ropivacaine, endogenous steroids and dihydroartemisinin

M Abbas - 2015 - stax.strath.ac.uk
The thesis consists of five chapters. The first chapter is general introduction to LC-MS,
separation technology and extraction methods. The second chapter describes the …