Two recent studies raised new concerns regarding cardiovascular (CV) risks with
testosterone (T) therapy. This article reviews those studies as well as the extensive literature …

A significant proportion of patients with type 2 diabetes mellitus have a low testosterone
level relative to reference ranges based on healthy young men. Only a small number of …

Aim The age-specific population profiles in men of circulating testosterone and its two
bioactive metabolites dihydrotestosterone (DHT) and estradiol (E2) across the adult lifespan …

Despite increased global interest in testosterone deficiency in men and its treatment with
testosterone therapy, practical aspects of care remain confusing to many practitioners …

Objectives Lower circulating androgens and poorer lung function are associated with
increased cardiovascular risk and mortality in men. The association between androgens and …

Context: Testosterone (T) levels have been associated with mortality, but controversy exists.
Objective: Our objective was to investigate associations between serum levels of total T …

Context: Epidemiologic studies suggest that endogenous testosterone (T) levels in males
may be implicated in cardiovascular disease (CVD), however further clarification is needed …

Additional randomized controlled trials are required to clarify the role of testosterone
supplementation in older men in the absence of pituitary or gonadal disease. Pending such …

Objective To determine the prevalence of thrombotic events and all-cause mortality in men
older than 65 years with hypogonadism treated with testosterone therapy (TST). Patients …

Objective Our objective was to characterize and evaluate prognostic implications of
circulating sex steroids in patients at different stages of chronic kidney disease (CKD) …