In addition to causing distress and disability to the individual, neuropsychiatric disorders are
also extremely expensive to society and governments. These disorders are both common …

Communication between the prefrontal cortex and subcortical nuclei underpins the control
and inhibition of behavior. However, the interactions in such pathways remain controversial …

Although characteristic motor symptoms of Parkinson's disease such as bradykinesia
typically improve under dopaminergic medication, deficits in higher motor control are less …

Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by a loss of dopaminergic neurons in the substantia nigra, as well as in other …

Objectives: Attenuation of adrenergic drive and cognitive enhancement, via stimulation of
alpha2 pre-and post-synaptic receptors, may selectively enhance executive performance in …

The motor manifestations of Parkinson's disease (PD) are secondary to a dopamine
deficiency in the striatum. However, the degenerative process in PD is not limited to the …

Reduction of dopamine agonist dose is the mainstay of treatment of ICBs. Other forms of
dopaminergic treatment such as deep brain stimulation or jejunal infusion are alternative …

Up to 50 percent of all Parkinson's disease (PD) patients develop symptoms of anxiety
during the course of their illness, a percentage that is much higher than in the general …