Host cell proteases: critical determinants of coronavirus tropism and pathogenesis
JK Millet, GR Whittaker - Virus research, 2015 - Elsevier
Coronaviruses are a large group of enveloped, single-stranded positive-sense RNA viruses
that infect a wide range of avian and mammalian species, including humans. The …
that infect a wide range of avian and mammalian species, including humans. The …
[HTML][HTML] Bat-to-human: spike features determining 'host jump'of coronaviruses SARS-CoV, MERS-CoV, and beyond
Both severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East
respiratory syndrome coronavirus (MERS-CoV) are zoonotic pathogens that crossed the …
respiratory syndrome coronavirus (MERS-CoV) are zoonotic pathogens that crossed the …
Protease inhibitors targeting coronavirus and filovirus entry
Y Zhou, P Vedantham, K Lu, J Agudelo, R Carrion Jr… - Antiviral research, 2015 - Elsevier
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus
and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins …
and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins …
Ebola Virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+ Endolysosomes Is a Rate …
RM Mingo, JA Simmons, CJ Shoemaker… - Journal of …, 2015 - Am Soc Microbiol
Ebola virus (EBOV) causes hemorrhagic fevers with high mortality rates. During cellular
entry, the virus is internalized by macropinocytosis and trafficked through endosomes until …
entry, the virus is internalized by macropinocytosis and trafficked through endosomes until …
Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants
M Meyer, I Jaspers - American Journal of Physiology-Lung …, 2015 - journals.physiology.org
The respiratory epithelium functions as a central orchestrator to initiate and organize
responses to inhaled stimuli. Proteases and antiproteases are secreted from the respiratory …
responses to inhaled stimuli. Proteases and antiproteases are secreted from the respiratory …
[PDF][PDF] Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection
M Esumi, M Ishibashi, H Yamaguchi, S Nakajima… - …, 2015 - Wiley Online Library
The human liver reacts to hepatitis C virus (HCV) with a balanced response consisting of
host anti‐and proviral activities. To explore these subtle host responses, we used …
host anti‐and proviral activities. To explore these subtle host responses, we used …
[PDF][PDF] UNDERSTANDING THE VIRAL-HOST INTERACTIONS OF NEWLY EMERGED AND HIGHLY PATHOGENIC HUMAN CORONAVIRUSES
NGOI WING - 2015 - core.ac.uk
UNDERSTANDING THE VIRAL-HOST INTERACTIONS OF NEWLY EMERGED AND
HIGHLY PATHOGENIC HUMAN CORONAVIRUSES NG OI WING (B.Sc.(Hons.), N Page 1 …
HIGHLY PATHOGENIC HUMAN CORONAVIRUSES NG OI WING (B.Sc.(Hons.), N Page 1 …
The protease/antiprotease balance determines influenza susceptibility and can be modified by oxidants and antioxidants
M Meyer - 2015 - cdr.lib.unc.edu
The respiratory epithelium functions as a central orchestrator to initiate and organize
responses to inhaled stimuli. Proteases and antiproteases are secreted from the respiratory …
responses to inhaled stimuli. Proteases and antiproteases are secreted from the respiratory …