Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse …
Background: Endocannabinoids modulate the glutamatergic excitatory transmission by
acting as retrograde messengers. A growing body of studies has reported that both signaling …
acting as retrograde messengers. A growing body of studies has reported that both signaling …
Withdrawal from Cocaine Self-administration and Yoked Cocaine Delivery Dysregulates Glutamatergic mGlu5 and NMDA Receptors in the Rat Brain
L Pomierny-Chamiolo, J Miszkiel, M Frankowska… - Neurotoxicity …, 2015 - Springer
In human addicts and in animal models, chronic cocaine use leads to numerous alterations
in glutamatergic transmission, including its receptors. The present study focused on …
in glutamatergic transmission, including its receptors. The present study focused on …
Dopamine and glutamate interaction mediates reinstatement of drug-seeking behavior by stimulation of the ventral subiculum
P Taepavarapruk, KA Butts… - International Journal of …, 2015 - academic.oup.com
Background: Drug addiction is a chronic brain disease characterized by recurrent episodes
of relapse to drug-seeking/-taking behaviors. The ventral subiculum, the primary output of …
of relapse to drug-seeking/-taking behaviors. The ventral subiculum, the primary output of …
Cocaine self‐administration enhances excitatory responses of pyramidal neurons in the rat medial prefrontal cortex to human immunodeficiency virus‐1 T at
WN Wayman, L Chen, TC Napier… - European Journal of …, 2015 - Wiley Online Library
The medial prefrontal cortex (mPFC) plays a critical role in reward‐motivated behaviors.
Repeated cocaine exposure dysregulates the dorsal mPFC, and this is thought to contribute …
Repeated cocaine exposure dysregulates the dorsal mPFC, and this is thought to contribute …
Episodic sucrose intake during food restriction increases synaptic abundance of AMPA receptors in nucleus accumbens and augments intake of sucrose following …
Weight-loss dieting often leads to loss of control, rebound weight gain, and is a risk factor for
binge pathology. Based on findings that food restriction (FR) upregulates sucrose-induced …
binge pathology. Based on findings that food restriction (FR) upregulates sucrose-induced …
COCAINE-BASED SIGNALING CHANGES IN THE NUCLEUS ACCUMBENS, LATERAL HABENULA, AND THALAMUS
PA Neumann - 2015 - d-scholarship.pitt.edu
The brain is an extraordinarily complex and organized system. Environmental information
reaches the brain via the sensory systems, and this information is processed to interpret and …
reaches the brain via the sensory systems, and this information is processed to interpret and …
Characterization of GABAergic projection from the ventral tegmental area to the nucleus accumbens: Effects of dopamine and cocaine
M Otaka - 2015 - d-scholarship.pitt.edu
Within the mesolimbic dopamine (DA) system, the VTA-to-NAc projection is essential for
many emotional and motivational responses, and is often targeted by drugs of abuse to …
many emotional and motivational responses, and is often targeted by drugs of abuse to …
[图书][B] The pathophysiological effects of cocaine and HIV-1proteins on the medial prefrontal cortex
WN Wayman - 2015 - search.proquest.com
Neuronal underpinnings of the cognitive decline and psychiatric disorders that can be
associated with HIV infection, even when peripheral viral load is controlled with antiretroviral …
associated with HIV infection, even when peripheral viral load is controlled with antiretroviral …
A Neurobiological Pathway That Mediates Stress-Induced Drug Use
O Vranjkovic - 2015 - epublications.marquette.edu
Cocaine addiction represents a tremendous health and financial burden on our society and
the high rate of relapse to cocaine use in abstinent addicts represents a major barrier to …
the high rate of relapse to cocaine use in abstinent addicts represents a major barrier to …