Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 …

The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily of
transcription factors, which exerts anti-proliferative and anti-apoptotic activities. The GR is …

FOXA1 expression correlates with the breast cancer luminal subtype and patient survival.
RNA and protein analysis of a panel of breast cancer cell lines revealed that BRCA1 …

The FOXA family of transcription factors regulates chromatin structure and gene expression
especially during embryonic development. In normal breast tissue FOXA1 acts throughout …

Background: FOXA1 expression is a good prognostic marker for endocrine therapy in
hormone-positive breast cancer. We retrospectively examined breast cancer patients with …

Background The prediction of breast cancer intrinsic subtypes has been introduced as a
valuable strategy to determine patient diagnosis and prognosis, and therapy response. The …

Peroxisome proliferator-activated receptor-gamma (PPAR γ) is an adopted orphan receptor
that belongs to the nuclear receptor superfamily of transcription factors. PPAR γ is regarded …

Recurrence and death in a significant number of patients with ERα-positive breast cancer
occurs 10–20 years after diagnosis. Prognostic markers for late events have been more …

Aim: Microarray studies identified a subgroup of molecular apocrine tumors (estrogen
receptor [ER] negative/androgen receptor [AR] positive) that express luminal genes …

Purpose Most estrogen receptor (ER)-positive breast cancer responds poorly to
chemotherapy and no single cost-effective biomarker capable of selecting chemosensitive …