Pseudomonas aeruginosa is the causative agent of chronic respiratory infections and is an
important pathogen of cystic fibrosis patients. Adaptive mutations play an essential role for …

Under growth-restricting conditions bacterial populations can rapidly evolve by a process
known as stationary-phase mutagenesis. Bacterial nonhomologous end-joining (NHEJ) …

In addition to its prominence in producing genetic diversity in bacterial species, homologous
recombination (HR) plays a key role in DNA repair and damage tolerance. The frequency of …

Alternative formats If you require this document in an alternative format, please contact:
openaccess@bath.ac.uk Page 1 University of Bath PHD The causes and consequences of a …

Alternations in the chemical structure of DNA molecule can have mutagenic or even fatal
consequences for a cell and need to be promptly repaired. DNA lesions occur …

Concurrent bacterial replication and transcription lead to conflicts between the two
machineries. These encounters, which impede replication and destabilize genomes, are …

Bacterial chromosomal replication initiates from a single origin of replication and proceeds
bidirectionally until completion at the terminus. Replication forks regularly encounter …