Cognitive impairments and depression: a critical review

M Roca, M Vives, E López-Navarro… - Actas espanolas de …, 2015 - actaspsiquiatria.es
Cognitive impairments are core symptoms of depressive disorders. We assess the
systematic reviews and meta-analysis studies published over the last 10 years (2004-2014) …

The involvement of TNF-α in cognitive dysfunction associated with major depressive disorder: an opportunity for domain specific treatments

B Bortolato, AF Carvalho… - Current …, 2015 - ingentaconnect.com
Major depressive disorder is a highly prevalent, chronic and recurring disorder, associated
with substantial impairment in cognitive and interpersonal functions. Accumulating evidence …

Ketamine as a promising prototype for a new generation of rapid‐acting antidepressants

CG Abdallah, LA Averill… - Annals of the New York …, 2015 - Wiley Online Library
The discovery of ketamine's rapid and robust antidepressant effects opened a window into a
new generation of antidepressants. Multiple controlled trials and open‐label studies have …

The neurocognitive profile of mood disorders–a review of the evidence and methodological issues

RJ Porter, LJ Robinson, GS Malhi… - Bipolar …, 2015 - Wiley Online Library
Objectives Cognitive abnormalities are an established part of the symptomatology of mood
disorders. However, questions still exist regarding the exact profile of these deficits in terms …

Major depressive disorder: mechanism-based prescribing for personalized medicine

PF Saltiel, DI Silvershein - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
Individual patients with depression present with unique symptom clusters–before, during,
and even after treatment. The prevalence of persistent, unresolved symptoms and their …

Indoleamine 2, 3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

JM Heisler, JC O'Connor - Brain, behavior, and immunity, 2015 - Elsevier
Cognitive dysfunction in depression is a prevalent and debilitating symptom that is poorly
treated by the currently available pharmacotherapies. Research over the past decade has …

Measuring cognitive function in MDD: emerging assessment tools

M Russo, K Mahon, KE Burdick - Depression and anxiety, 2015 - Wiley Online Library
Cognitive impairment is emerging as an important therapeutic target in patients with
psychiatric illnesses, including major depressive disorder (MDD). The objective of this …

Trait rumination, depression, and executive functions in early adolescence

CA Wagner, LB Alloy, LY Abramson - Journal of youth and adolescence, 2015 - Springer
Although deficits in executive functions have been linked with both depression and
rumination in adulthood, the nature of the relationship between these constructs is not well …

Cognitive function after clinical remission in patients with melancholic and non-melancholic depression: a 6 month follow-up study

M Roca, S Monzón, M Vives, E López-Navarro… - Journal of affective …, 2015 - Elsevier
Background Cognitive symptoms are core symptoms with an impact on functioning in
depression. Remission is considered as the main objective of the management and …

Subcortical volumes differentiate major depressive disorder, bipolar disorder, and remitted major depressive disorder

MD Sacchet, EE Livermore, JE Iglesias… - Journal of psychiatric …, 2015 - Elsevier
Subcortical gray matter regions have been implicated in mood disorders, including Major
Depressive Disorder (MDD) and Bipolar Disorder (BD). It is unclear, however, whether or …