In some patient groups, including critically ill patients, the pharmacokinetics of β-lactam
antibiotics may be profoundly disturbed due to pathophysiological changes in distribution …

Population pharmacokinetic analyses can be applied to predict optimized dosages for
individual patients. The aim of this study was to compare the prediction performance of the …

The precision of the model parameters, and hence the model predictions, is dependent on
the experimental design. A limited study design is dictated by cost and, for in vivo studies …

Background Recommendations on drug dose adjustment in patients with renal impairment
may vary between the references. It is often unknown which approach the dosing schemes …

Doing a PhD is always a challenge. To finish successfully, you need to be inspired by your
topic, and you need to have a good deal of perseverance and creativity. However, doing …

* Sector for Pharmacy,‡ Clinic of Anesthesiology and Intensive Therapy,|| National Poison
Control Center,¶ Institute for Scientific Information, Military Medical Academy, Belgrade …

Despite the scientific and technological breakthroughs that have graced the last century, the
path to bringing a drug to the market is fraught with risk and remains an expensive and time …