[HTML][HTML] Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance
SK Denduluri, O Idowu, Z Wang, Z Liao, Z Yan… - Genes & diseases, 2015 - Elsevier
One of the greatest obstacles to current cancer treatment efforts is the development of drug
resistance by tumors. Despite recent advances in diagnostic practices and surgical …
resistance by tumors. Despite recent advances in diagnostic practices and surgical …
EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition
Y Zhang, SX Wang, JW Ma, HY Li, JC Ye… - Journal of neuro …, 2015 - Springer
Rational: Combination therapy to inhibit cancer stem cells may have important clinical
implications. Here, we examine the molecular mechanisms by which epigallocatechin …
implications. Here, we examine the molecular mechanisms by which epigallocatechin …
[HTML][HTML] MicroRNA-542-3p suppresses tumor cell invasion via targeting AKT pathway in human astrocytoma
J Cai, JJ Zhao, N Zhang, X Xu, R Li, Y Yi, L Fang… - Journal of Biological …, 2015 - ASBMB
The molecular mechanism underlying constitutive activation of AKT signaling, which plays
essential roles in astrocytoma progression, is not fully characterized. Increasing numbers of …
essential roles in astrocytoma progression, is not fully characterized. Increasing numbers of …
MiR-661 inhibits glioma cell proliferation, migration and invasion by targeting hTERT
Z Li, Y Liu, H Diao, J Ma, Y Yao - Biochemical and biophysical research …, 2015 - Elsevier
In this study, we analyzed the functional role of miR-661 in glioma cell proliferation,
migration and invasion. We found that overexpression of miR-661 obviously suppressed the …
migration and invasion. We found that overexpression of miR-661 obviously suppressed the …
[HTML][HTML] Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death
JC Jagtap, D Parveen, RD Shah, A Desai, D Bhosale… - FEBS open bio, 2015 - Elsevier
Glioblastoma multiforme (GBM) is the most malignant form of brain tumor and is associated
with resistance to conventional therapy and poor patient survival. Prostate apoptosis …
with resistance to conventional therapy and poor patient survival. Prostate apoptosis …
[HTML][HTML] Chemical library screening and structure-function relationship studies identify bisacodyl as a potent and selective cytotoxic agent towards quiescent human …
M Zeniou, M Fève, S Mameri, J Dong, C Salomé… - PloS one, 2015 - journals.plos.org
Cancer stem-like cells reside in hypoxic and slightly acidic tumor niches. Such
microenvironments favor more aggressive undifferentiated phenotypes and a slow growing" …
microenvironments favor more aggressive undifferentiated phenotypes and a slow growing" …
Chemosensitizing effects and Molecular Dynamic study of Substituted Benzo1, 3-oxazines as Novel DNA-PK, PI3K Inhibitors
R Suraj - 2015 - opal.latrobe.edu.au
Submission note: A thesis submitted in total fulfilment of the requirements for the Degree of
Doctor of Philosophy to the School of Pharmacy and Applied Science, Faculty of Science …
Doctor of Philosophy to the School of Pharmacy and Applied Science, Faculty of Science …