Dynamic and fluid–structure interaction simulations of bioprosthetic heart valves using parametric design with T-splines and Fung-type material models

MC Hsu, D Kamensky, F Xu, J Kiendl, C Wang… - Computational …, 2015 - Springer
This paper builds on a recently developed immersogeometric fluid–structure interaction
(FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances …

Coronary flow impacts aortic leaflet mechanics and aortic sinus hemodynamics

BL Moore, LP Dasi - Annals of biomedical engineering, 2015 - Springer
Mechanical stresses on aortic valve leaflets are well-known mediators for initiating
processes leading to calcific aortic valve disease. Given that non-coronary leaflets calcify …

Stability and conservation properties of collocated constraints in immersogeometric fluid-thin structure interaction analysis

D Kamensky, JA Evans, MC Hsu - Communications in Computational …, 2015 - cambridge.org
The purpose of this study is to enhance the stability properties of our recently-developed
numerical method [D. Kamensky, M.-C. Hsu, D. Schillinger, JA Evans, A. Aggarwal, Y …

Influence of anatomic valve conditions and coronary flow on aortic sinus hemodynamics

BL Moore - 2015 - search.proquest.com
Heart disease is the leading cause of death in the US, and aortic valve stenosis represents a
significant portion of this disease. While the specific causes of stenosis are not entirely clear …

Valvular Endothelial Mechanobiology

S Srigunapalan, CA Simmons - Mechanobiology of the …, 2015 - api.taylorfrancis.com
The human heart contains four valves that ensure unidirectional blood flow throughout the
cardiac cycle. The semilunar valves (pulmonary on the right side and aortic on the left) …