[HTML][HTML] RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

CM Mikelis, M Simaan, K Ando, S Fukuhara… - Nature …, 2015 - nature.com
Histamine-induced vascular leakage is an integral component of many highly prevalent
human diseases, including allergies, asthma and anaphylaxis. Yet, how histamine induces …

Requisite role for Nck adaptors in cardiovascular development, endothelial-to-mesenchymal transition, and directed cell migration

DL Clouthier, CN Harris, RA Harris… - … and cellular biology, 2015 - Taylor & Francis
Development of the cardiovascular system is critically dependent on the ability of endothelial
cells (ECs) to reorganize their intracellular actin architecture to facilitate migration, adhesion …

[HTML][HTML] Circulating angiopopietin-1 correlates with the clinical course of multiple organ dysfunction syndrome and mortality in patients with severe sepsis

SM Lin, FT Chung, CH Kuo, PC Chou, TY Wang… - Medicine, 2015 - journals.lww.com
Circulating Angiopopietin-1 Correlates With the Clinical Cou... : Medicine Circulating
Angiopopietin-1 Correlates With the Clinical Course of Multiple Organ Dysfunction …

The angiopoietin—tie system: common signaling pathways for angiogenesis, cancer, and inflammation

Y Reiss, A Scholz, KH Plate - Endothelial Signaling in Development and …, 2015 - Springer
Angiopoietins and their cognate tyrosine kinase receptors have been recognized as crucial
cytokines that control angiogenic growth and remodeling. In addition to their established …

PET molecular imaging of angiogenesis with a multiple tyrosine kinase receptor-targeted agent in a rat model of myocardial infarction

S Dissoki, G Abourbeh, O Salnikov, E Mishani… - Molecular Imaging and …, 2015 - Springer
Purpose Angiogenesis plays a major role in tissue remodeling and repair after myocardial
infarction (MI), and imaging it could provide information on the healing process. During …

Pericytes in vascular development and function

R Daneman, A Keller - Endothelial Signaling in Development and Disease, 2015 - Springer
Pericytes are perivascular cells that line the abluminal surface of the microvasculature.
Recent years have witnessed tremendous progress in understanding the function of these …

Tie2 表达载体的构建及其稳定转染SKOV3 细胞系的建立

陈雅静, 许淑茹, 付达华, 许秀宽, 舒伟 - 内科, 2015 - cqvip.com
目的构建人Tie2 基因真核表达载体, 并建立稳定过表达rrie2 基因的SKOV3 细胞系. 方法采用RT—
PCR 方法从人肝癌细胞BEL-7402 细胞系中扩增Tie2 基因编码区(cDNA), 将产物克隆至pEGFP …

Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function

GJ Bix - US Patent 9,072,713, 2015 - Google Patents
2014-01-31 Assigned to THE TEXAS A&M UNIVERSITY SYSTEM reassignment THE
TEXAS A&M UNIVERSITY SYSTEM CORRECTIVE ASSIGNMENT TO CORRECT THE …

Marine sponge derived antiangiogenic compounds

AR Quesada, B Martínez-Poveda… - Handbook of Anticancer …, 2015 - Springer
Angiogenesis plays an essential role in tumor growth, invasion, and metastasis. Inhibition of
angiogenesis has become a major challenge in the development of new anticancer agents …

Implication de la transition endothélium-mésenchyme dans le développement des complications digestives des radiothérapies.

E Mintet - 2015 - theses.hal.science
La fibrose digestive est une complication secondaire tardive de la radiothérapie dans 5 à
10% des patients traités pour des tumeurs de la sphère abdomino-pelvienne. Elle est …