Diagnostic Tests for Childhood Tuberculosis: Past Imperfect,... : The Pediatric Infectious
Disease Journal Diagnostic Tests for Childhood Tuberculosis: Past Imperfect, Present Tense …

Tuberculosis (TB) is a premier example of a disease complex with pathogens primarily
affecting humans (ie, Mycobacterium tuberculosis) or livestock and wildlife (ie …

Rationale: Current immunodiagnostic tests for tuberculosis (TB), including the tuberculin
skin test and IFN-γ release assay (IGRA), have significant limitations, which include their …

Identifying those Mycobacterium tuberculosis latent-infected individuals most at risk of
developing active tuberculosis (TB) using routine clinical and laboratory tests remains a …

Tuberculosis (TB) remains a global health threat, with over a third of the world population
suffering from the disease, and 1.5 million deaths due to the disease in 2013 alone. Despite …

Rationale: The identification of patients with latent tuberculosis infection, who are at higher
risk to develop active disease, is an important component of disease control. Objectives: We …

Rationale: Children who are young, malnourished, and infected with HIV have significant
risk of tuberculosis (TB) morbidity and mortality following TB infection. Treatment of TB …

The enormous reservoir of latent TB infection (LTBI) poses a major hurdle for global TB
control. The existing Tuberculin skin test (TST) and IFN-γ release assays (IGRAs) are found …

Although there have been many recent advances in Tuberculosis (TB) detection
technologies, there still remains a major need to develop simpler point-of-care techniques …

SETTING: A tertiary care academic medical centre. OBJECTIVE: To evaluate the clinical
usefulness of CXC chemokine receptor 3 (CXCR3) ligands in active pulmonary tuberculosis …