Role of corticostriatal circuits in context-induced reinstatement of drug seeking

NJ Marchant, K Kaganovsky, Y Shaham, JM Bossert - Brain research, 2015 - Elsevier
Drug addiction is characterized by persistent relapse vulnerability during abstinence. In
abstinent drug users, relapse is often precipitated by re-exposure to environmental contexts …

Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary …

D Caprioli, M Venniro, T Zeric, X Li, S Adhikary… - Biological …, 2015 - Elsevier
Background Cue-induced methamphetamine craving increases after prolonged forced
(experimenter-imposed) abstinence from the drug (incubation of methamphetamine …

The central amygdala nucleus is critical for incubation of methamphetamine craving

X Li, T Zeric, S Kambhampati, JM Bossert… - …, 2015 - nature.com
Cue-induced methamphetamine seeking progressively increases after withdrawal but
mechanisms underlying this 'incubation of methamphetamine craving'are unknown. Here we …

Persistent palatable food preference in rats with a history of limited and extended access to methamphetamine self‐administration

D Caprioli, T Zeric, EB Thorndike… - Addiction biology, 2015 - Wiley Online Library
Recent studies have shown that when given a mutually exclusive choice between cocaine
and palatable foods, most rats prefer the non‐drug rewards over cocaine. Here, we used a …

Effect of yohimbine on reinstatement of operant responding in rats is dependent on cue contingency but not food reward history

YW Chen, KA Fiscella, SZ Bacharach… - Addiction …, 2015 - Wiley Online Library
Yohimbine is an alpha‐2 adrenoceptor antagonist that has been used in numerous studies
as a pharmacological stressor in rodents, monkeys and humans. Recently, yohimbine has …

On the positive and negative affective responses to cocaine and their relation to drug self-administration in rats

A Ettenberg, V Fomenko, K Kaganovsky, K Shelton… - …, 2015 - Springer
Rationale Acute cocaine administration produces an initial rewarding state followed by a
dysphoric/anxiogenic “crash.” Objective The objective of this study was to determine whether …

Measures of the aversive effects of drugs: A comparison of conditioned taste and place aversions

JK Gore-Langton, SM Flax, RL Pomfrey… - Pharmacology …, 2015 - Elsevier
The present experiments directly compared the ability of the conditioned taste and place
aversion designs (CTA and CPA, respectively) to measure the aversive effects of lithium …

[HTML][HTML] Effect of the novel positive allosteric modulator of mGluR2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary abstinence in a rat …

D Caprioli, M Venniro, T Zeric, X Li, S Adhikary… - Biological …, 2015 - ncbi.nlm.nih.gov
Background Cue-induced methamphetamine craving increases after prolonged forced
(experimenter-imposed) abstinence from the drug (incubation of methamphetamine …

[HTML][HTML] Motivated explanation

R Patterson, JT Operskalski, AK Barbey - Frontiers in human …, 2015 - frontiersin.org
Although motivation is a well-established field of study in its own right, and has been fruitfully
studied in connection with attribution theory and belief formation under the heading of …

CRF antagonism within the ventral tegmental area but not the extended amygdala attenuates the anxiogenic effects of cocaine in rats

A Ettenberg, SW Cotten, MA Brito, AK Klein… - Pharmacology …, 2015 - Elsevier
In addition to its initial rewarding effects, cocaine has been shown to produce profound
negative/anxiogenic actions. Recent work on the anxiogenic effects of cocaine has …