Stem cell based therapies for age-related macular degeneration: the promises and the challenges
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …
Hurdles to clinical translation of human induced pluripotent stem cells
E Neofytou, CG O'Brien, LA Couture… - The Journal of clinical …, 2015 - Am Soc Clin Investig
Human pluripotent stem cells are known to have the capacity to renew indefinitely, being
intrinsically able to differentiate into many different cell types. These characteristics have …
intrinsically able to differentiate into many different cell types. These characteristics have …
Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies
JA Heslop, TG Hammond, I Santeramo… - Stem cells …, 2015 - academic.oup.com
The field of stem cell therapeutics is moving ever closer to widespread application in the
clinic. However, despite the undoubted potential held by these therapies, the balance …
clinic. However, despite the undoubted potential held by these therapies, the balance …
Human embryonic stem cell cultivation: historical perspective and evolution of xeno-free culture systems
N Desai, P Rambhia, A Gishto - Reproductive Biology and Endocrinology, 2015 - Springer
Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based
therapies that are capable of restoring lost cell and tissue function. These unique cells are …
therapies that are capable of restoring lost cell and tissue function. These unique cells are …
Banking on iPSC-is it doable and is it worthwhile
S Solomon, F Pitossi, MS Rao - Stem Cell Reviews and Reports, 2015 - Springer
The discovery of induced pluripotent stem cells (iPSCs) and concurrent development of
protocols for their cell-type specific differentiation have revolutionized studies of diseases …
protocols for their cell-type specific differentiation have revolutionized studies of diseases …
The safety of human pluripotent stem cells in clinical treatment
OE Simonson, A Domogatskaya, P Volchkov… - Annals of …, 2015 - Taylor & Francis
Human pluripotent stem cells (hPSCs) have practically unlimited proliferation potential and a
capability to differentiate into any cell type in the human body. Since the first derivation in …
capability to differentiate into any cell type in the human body. Since the first derivation in …
Safety of allogeneic bone marrow derived mesenchymal stromal cell therapy in renal transplant recipients: the neptune study
MEJ Reinders, GJ Dreyer, JR Bank, H Roelofs… - Journal of translational …, 2015 - Springer
Background Mesenchymal stromal cells (MSC) may serve as an attractive therapy in renal
transplantation due to their immunosuppressive and reparative properties. While most …
transplantation due to their immunosuppressive and reparative properties. While most …
[HTML][HTML] Allogenic banking of dental pulp stem cells for innovative therapeutics
PY Collart-Dutilleul, F Chaubron, J De Vos… - World journal of stem …, 2015 - ncbi.nlm.nih.gov
Medical research in regenerative medicine and cell-based therapy has brought encouraging
perspectives for the use of stem cells in clinical trials. Multiple types of stem cells, from …
perspectives for the use of stem cells in clinical trials. Multiple types of stem cells, from …
Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cells
Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced
pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different …
pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different …
The molecular karyotype of 25 clinical-grade human embryonic stem cell lines
MA Canham, A Van Deusen, DR Brison… - Scientific reports, 2015 - nature.com
The application of human embryonic stem cell (hESC) derivatives to regenerative medicine
is now becoming a reality. Although the vast majority of hESC lines have been derived for …
is now becoming a reality. Although the vast majority of hESC lines have been derived for …