Obesity-related insulin resistance: implications for the surgical patient
N Tewari, S Awad, IA Macdonald… - International journal of …, 2015 - nature.com
In healthy surgical patients, preoperative fasting and major surgery induce development of
insulin resistance (IR). IR can be present in up to 41% of obese patients without diabetes …
insulin resistance (IR). IR can be present in up to 41% of obese patients without diabetes …
[HTML][HTML] Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects
H Zhang, E Sturchler, J Zhu, A Nieto… - Nature …, 2015 - nature.com
Abstract Glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonists have emerged as
treatment options for type 2 diabetes mellitus (T2DM). GLP-1R signals through G-protein …
treatment options for type 2 diabetes mellitus (T2DM). GLP-1R signals through G-protein …
Adding liraglutide to lifestyle changes, metformin and testosterone therapy boosts erectile function in diabetic obese men with overt hypogonadism
VA Giagulli, MD Carbone, MI Ramunni, B Licchelli… - …, 2015 - Wiley Online Library
The aim of this retrospective observational study was to evaluate whether adding liraglutide
to lifestyle changes, metformin (Met) and testosterone replacement therapy (TRT), by means …
to lifestyle changes, metformin (Met) and testosterone replacement therapy (TRT), by means …
GLP-1 increases preovulatory LH source and the number of mature follicles, as well as synchronizing the onset of puberty in female rats
V Outeiriño-Iglesias, M Romaní-Pérez… - …, 2015 - academic.oup.com
Control of estrous cycle and reproductive capacity involves a large number of central and
peripheral factors, integrating numerous nutritional and metabolic signals. Here we show …
peripheral factors, integrating numerous nutritional and metabolic signals. Here we show …
Effect of sitagliptin on intrahepatic lipid content and body fat in patients with type 2 diabetes
H Kato, Y Nagai, A Ohta, A Tenjin, Y Nakamura… - Diabetes research and …, 2015 - Elsevier
Aims To evaluate the effect of the DPP-4 inhibitor sitagliptin on intrahepatic lipid (IHL)
content and body fat in overweight Japanese patients with type 2 diabetes. Methods A …
content and body fat in overweight Japanese patients with type 2 diabetes. Methods A …
[HTML][HTML] Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, on Adiposity with Increased Ppargc1a in White Adipose Tissue in Obese Mice
YN Chae, TH Kim, MK Kim, CY Shin, IH Jung… - PLoS …, 2015 - journals.plos.org
Although dipeptidyl peptidase 4 (DPP4) is an adipokine known to positively correlate with
adiposity, the effects of pharmacological DPP4 inhibition on body composition have not …
adiposity, the effects of pharmacological DPP4 inhibition on body composition have not …
Exendin-4 improves thermogenic capacity by regulating fat metabolism on brown adipose tissue in mice with diet-induced obesity
Q Wei, L Li, J Chen, S Wang… - Annals of Clinical & …, 2015 - Assoc Clin Scientists
Objective This study aimed to investigate the benefits of exendin-4 treatment on brown
adipose tissue (BAT) in C57BL/6J mice with high-fat diet (HFD)-induced obesity. Methods …
adipose tissue (BAT) in C57BL/6J mice with high-fat diet (HFD)-induced obesity. Methods …
[HTML][HTML] High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats
M Zhang, C Liu, M Hu, J Zhang, P Xu, F Li… - Journal of …, 2015 - Elsevier
Evidence has shown that hyperlipidemia is associated with retinoid dyshomeostasis. In liver,
retinol is mainly oxidized to retinal by retinol dehydrogenases (RDHs) and alcohol …
retinol is mainly oxidized to retinal by retinol dehydrogenases (RDHs) and alcohol …
GLP-1 receptor agonist increases the expression of CTRP3, a novel adipokine, in 3T3-L1 adipocytes through PKA signal pathway
X Li, L Jiang, M Yang, Y Wu, S Sun, J Sun - Journal of endocrinological …, 2015 - Springer
Objective To investigate the effects of Exendin-4 (Ex-4), a glucagon-like peptide-1 (GLP-1)
receptor agonist, on the expression of C1q/TNF-related protein-3 (CTRP3), a novel …
receptor agonist, on the expression of C1q/TNF-related protein-3 (CTRP3), a novel …
GLP-1 与2 型糖尿病脂代谢异常及临床处理
杜玉茗， 刘赫 - 实用糖尿病杂志, 2015 - cqvip.com
GLP-1与2型糖尿病脂代谢异常及临床处理-[维普官方网站]-www.cqvip.com-维普网 我的维普
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