Spinal cord injury (SCI) results in devastating neurological and pathological consequences,
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …

One of the big challenges in neuroscience that remains to be understood is why the central
nervous system is not able to regenerate to the extent that the peripheral nervous system …

Background Neurofilaments (Nf) are major structural proteins that occur exclusively in
neurons. In spinal cord injury (SCI), the severity of disease is quantified by clinical measures …

In prior analyses of the effectiveness of methylprednisolone for the treatment of patients with
acute traumatic spinal cord injuries (TSCIs), the prognostic importance of patients' …

Abstract Interleukin-33 (IL-33) is a member of the interleukin-1 cytokine family and highly
expressed in the naïve mouse brain and spinal cord. Despite the fact that IL-33 is known to …

Background Necroptosis is an emerging programmed necrosis other than traditional
necrosis and apoptosis. Until recently, there have not been studies that have investigated a …

Abstract Non-coding RNAs (ncRNAs), especially microRNAs (miRNAs) and long non-coding
RNAs (lncRNAs), have attracted much attention since their regulatory roles in diverse cell …

Spinal cord injury (SCI) has been implicated in neural cell loss and consequently functional
motor and sensory impairment. In this study, we propose an alginate-based neurobridge …

After spinal cord injury (SCI), secondary damage caused by oxidative stress, inflammation,
and ischemia leads to neurological deterioration. In recent years, therapeutic approaches to …

Introduction Ganoderma lucidum (G. lucidum) is a mushroom belonging to the polyporaceae
family of Basidiomycota and has widely been used as a traditional medicine for thousands of …