Agomelatine is an antidepressant with a unique mechanism of action. Since its marketing in
2009, concerns have been raised regarding its potential to induce liver injury. The authors …

Background Although many generalized anxiety disorder (GAD) patients respond to the
available pharmacological treatments, nearly half of them do not present the expected …

The impressive but sad list of over forty clinical studies using various cytotoxic
chemotherapies published in the last few years has failed to increase median survival of …

Agomelatine is an antidepressant with a distinct pharmacological mechanism of action as an
MT1 and MT2 receptor agonist and as a 5-HT 2C receptor antagonist. We evaluated the …

Background Major depressive disorder (MDD) is a mental disorder characterized by
episodes of depressed mood, loss of interest or pleasure, feeling of guilt or low self-esteem …

Objective To evaluate the effect of cognitive therapy on biological rhythm and depressive
and anxious symptoms in a twelve-month follow-up period. In addition, correlations between …

Introduction Although a growing selection of antidepressants is available, a significant
number of patients do not reach clinical remission, despite multiple trials. Data concerning …

Agomelatine is a melatonergic anti-depressant. A stability-indicating high performance liquid
chromatographic technique was developed for the determination of Agomelatine in …

В статье с позиций междисциплинарного подхода обсуждаются клиническое
оформление, специфика диагностики и терапии одного из вариантов …