Stimuli‐responsive polymeric nanoparticles for nanomedicine

CIC Crucho - ChemMedChem, 2015 - Wiley Online Library
Nature continues to be the ultimate in nanotechnology, where polymeric nanometer‐scale
architectures play a central role in biological systems. Inspired by the way nature forms …

Trigger responsive polymeric nanocarriers for cancer therapy

S Kaur, C Prasad, B Balakrishnan, R Banerjee - Biomaterials science, 2015 - pubs.rsc.org
Conventional chemotherapy for the treatment of cancer has limited specificity when
administered systemically and is often associated with toxicity issues. Enhanced …

Multi‐stimuli‐responsive polymeric materials

S Guragain, BP Bastakoti, V Malgras… - … A European Journal, 2015 - Wiley Online Library
Stimuli‐responsive materials are of immense importance because of their ability to undergo
alteration of their properties in response to their environment. The properties of such …

Glycyrrhetinic acid-mediated polymeric drug delivery targeting the acidic microenvironment of hepatocellular carcinoma

J Zhang, M Zhang, J Ji, X Fang, X Pan, Y Wang… - Pharmaceutical …, 2015 - Springer
Purpose The major hurdle of current drug carrier against hepatocellular carcinoma (HCC) is
the lack of specific and selective drug delivery to HCC. In this study, a novel glycyrrhetinic …

Superparamagnetic reduction/pH/temperature multistimuli-responsive nanoparticles for targeted and controlled antitumor drug delivery

J Zeng, P Du, L Liu, J Li, K Tian, X Jia… - Molecular …, 2015 - ACS Publications
Multistimuli-responsive polymeric nanoparticles with core–shell architecture were prepared
by coating superparamagnetic Fe3O4 nanoparticle cores with reduction/pH dual-responsive …

Efficient reduction and pH co-triggered DOX-loaded magnetic nanogel carrier using disulfide crosslinking

J Huang, Y Xue, N Cai, H Zhang, K Wen, X Luo… - Materials Science and …, 2015 - Elsevier
To reduce leakage on the drug-delivery pathway to minimize side effect of reduction or pH
sensitive drug delivery systems, we designed a glutathione (GSH)/pH co-triggered magnetic …

Polymer-block-polypeptides and polymer-conjugated hybrid materials as stimuli-responsive nanocarriers for biomedical applications

JV John, RP Johnson, MS Heo… - Journal of …, 2015 - ingentaconnect.com
Stimuli-responsive nanocarriers are a class of soft materials that includes natural polymers,
synthetic polymers, and polypeptides. Recently, modern synthesis tools such as atom …

Cancer targeting: responsive polymers for stimuli-sensitive drug delivery

S Bhatnagar, VVK Venuganti - Journal of Nanoscience and …, 2015 - ingentaconnect.com
Effective treatment of cancer is limited by the lack of delivery technology to specifically and
efficiently deliver chemotherapeutic agents within the tumor vicinity. The tumor targeting …

Reduction-triggered release of paclitaxel from in situ formed biodegradable core-cross-linked micelles

W Zhu, Y Wang, X Cai, G Zha, Q Luo, R Sun… - Journal of Materials …, 2015 - pubs.rsc.org
Paclitaxel-loaded reduction-responsive core-crosslinked micelles were prepared in situ in
aqueous media via “click” chemistry. An amphiphilic block copolymer with multiple pendant …

Chemical encoding of amphiphilic copolymers for a dual controlled release from their assemblies

LP Lv, Y Zhao, K Landfester, D Crespy - Polymer Chemistry, 2015 - pubs.rsc.org
Amphiphilic random copolymers are designed to bear a corrosion inhibitor as cleavable side
group, which can be released upon activation by chemical reduction. Polymer nanoparticles …