Bioavailability of dietary polyphenols: Factors contributing to their clinical application in CNS diseases

MD Pandareesh, RB Mythri, MMS Bharath - Neurochemistry international, 2015 - Elsevier
The anatomical location of the central nervous system (CNS) renders it immunologically and
pharmacologically privileged due to the blood brain barrier (BBB). Although this limits the …

[PDF][PDF] Dendrosomal nano-curcumin, the novel formulation to improve the anticancer properties of curcumin

BM TAHMASEBI, MV ERFANI, E Babaei, F NAJAFI… - 2015 - sid.ir
Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with
established anticancer properties. However, curcumin benefits have been impaired by its …

[HTML][HTML] Curcumin-Encapsulated Polymeric Micelles Suppress the Development of Colon Cancer In Vitro and In Vivo

X Yang, Z Li, N Wang, L Li, L Song, T He, L Sun… - Scientific reports, 2015 - nature.com
To develop injectable formulation and improve the stability of curcumin (Cur), Cur was
encapsulated into monomethyl poly (ethylene glycol)-poly (ε-caprolactone)-poly …

Dual-drug delivery of curcumin and platinum drugs in polymeric micelles enhances the synergistic effects: a double act for the treatment of multidrug-resistant cancer

W Scarano, P De Souza, MH Stenzel - Biomaterials science, 2015 - pubs.rsc.org
Combinational chemotherapy is often used to prevent drug induced resistance in cancer.
The aim of this work is to test whether the co-delivery of drugs within one nanoparticle can …

Gum arabic-curcumin conjugate micelles with enhanced loading for curcumin delivery to hepatocarcinoma cells

PR Sarika, NR James, PRA Kumar, DK Raj… - Carbohydrate …, 2015 - Elsevier
Curcumin is conjugated to gum arabic, a highly water soluble polysaccharide to enhance
the solubility and stability of curcumin. Conjugation of curcumin to gum arabic is confirmed …

A novel approach to arthritis treatment based on resveratrol and curcumin co-encapsulated in lipid-core nanocapsules: In vivo studies

K Coradini, RB Friedrich, FN Fonseca… - European Journal of …, 2015 - Elsevier
Resveratrol and curcumin are two natural polyphenols extensively used due to their
remarkable anti-inflammatory activity. The present work presents an inedited study of the in …

Encapsulation of curcumin in diblock copolymer micelles for cancer therapy

AM Alizadeh, M Sadeghizadeh, F Najafi… - BioMed research …, 2015 - Wiley Online Library
Application of nanoparticles has recently promising results for water insoluble agents like
curcumin. In this study, we synthesized polymeric nanoparticle‐curcumin (PNPC) and then …

Amphiphilic zein hydrolysate as a novel nano-delivery vehicle for curcumin

YH Wang, JM Wang, XQ Yang, J Guo, Y Lin - Food & function, 2015 - pubs.rsc.org
In this paper, we developed amphiphilic zein hydrolysate (ZH) as a novel delivery vehicle,
which could be used for preparing curcumin (Cur) nanocomplexes. These ZH–Cur …

Preparation of biodegradable PCL particles via double emulsion evaporation method using ultrasound technique

M Iqbal, JP Valour, H Fessi, A Elaissari - Colloid and Polymer Science, 2015 - Springer
Polymeric nanoparticles have attracted growing attention because of their unique properties
and extensive application. In this study, polycaprolactone (PCL) nanoparticles were …

A slow-release system of bacterial cellulose gel and nanoparticles for hydrophobic active ingredients

Y Numata, L Mazzarino, R Borsali - International journal of pharmaceutics, 2015 - Elsevier
A combination of bacterial cellulose (BC) gel and amphiphilic block copolymer nanoparticles
was investigated as a drug delivery system (DDS) for hydrophobic active ingredients. Poly …