The role of surgery in the management of patients with diffuse low grade glioma: a systematic review and evidence-based clinical practice guideline
Question Should patients with imaging suggestive of low grade glioma (LGG) undergo
observation versus treatment involving a surgical procedure? Target population These …
observation versus treatment involving a surgical procedure? Target population These …
Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period
OBJECT Awake craniotomy is currently a useful surgical approach to help identify and
preserve functional areas during cortical and subcortical tumor resections. Methodologies …
preserve functional areas during cortical and subcortical tumor resections. Methodologies …
Localizing seizure-susceptible brain regions associated with low-grade gliomas using voxel-based lesion-symptom mapping
Background Patients afflicted with low-grade glioma (LGG) frequently suffer from seizures.
The mechanisms of seizure initiation in these patients remain poorly understood. Tumor …
The mechanisms of seizure initiation in these patients remain poorly understood. Tumor …
GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor‐associated epilepsy
Seizures frequently accompany gliomas and often escalate to peritumoral epilepsy.
Previous work revealed the importance of tumor‐derived excitatory glutamate (Glu) release …
Previous work revealed the importance of tumor‐derived excitatory glutamate (Glu) release …
Neurocognitive function in newly diagnosed low-grade glioma patients undergoing surgical resection with awake mapping techniques
CA Racine, J Li, AM Molinaro, N Butowski… - Neurosurgery, 2015 - journals.lww.com
BACKGROUND: Low-grade glioma (LGG) patients have increased life expectancy, so
interest is high in the treatments that maximize cognition and quality of life. OBJECTIVE: To …
interest is high in the treatments that maximize cognition and quality of life. OBJECTIVE: To …
Seizure outcome after radiotherapy and chemotherapy in low-grade glioma patients: a systematic review
JAF Koekkoek, M Kerkhof, L Dirven… - Neuro …, 2015 - academic.oup.com
There is growing evidence that antitumor treatment contributes to better seizure control in
low-grade glioma patients. We performed a systematic review of the current literature on …
low-grade glioma patients. We performed a systematic review of the current literature on …
IDH1/2 mutation is associated with seizure as an initial symptom in low-grade glioma: a report of 311 Chinese adult glioma patients
Z Zhong, Z Wang, Y Wang, G You, T Jiang - Epilepsy research, 2015 - Elsevier
Background Seizure commonly presents as an initial symptom and plays an important role
in the clinical presentation and quality of life of patients with low-grade glioma (LGG). To …
in the clinical presentation and quality of life of patients with low-grade glioma (LGG). To …
Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide
JAF Koekkoek, L Dirven, JJ Heimans… - Journal of Neurology …, 2015 - jnnp.bmj.com
Background Seizures are a common symptom in patients with low-grade glioma (LGG),
negatively influencing quality of life, if uncontrolled. Besides antiepileptic drugs, antitumour …
negatively influencing quality of life, if uncontrolled. Besides antiepileptic drugs, antitumour …
Is there a risk of seizures in “preventive” awake surgery for incidental diffuse low-grade gliomas?
GL de Oliveira Lima, H Duffau - Journal of neurosurgery, 2015 - thejns.org
OBJECT Although a large amount of data supports resection for symptomatic diffuse low-
grade glioma (LGG), the therapeutic strategy regarding incidental LGG (ILGG) is still a matter …
grade glioma (LGG), the therapeutic strategy regarding incidental LGG (ILGG) is still a matter …