The non–small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome

R Remark, C Becker, JE Gomez, D Damotte… - American journal of …, 2015 - atsjournals.org
Solid tumors, beyond mere accumulation of cancer cells, form a complex ecosystem
consisting of normal epithelial cells, fibroblasts, blood and lymphatic vessels, structural …

[HTML][HTML] Therapeutic potential and challenges of natural killer cells in treatment of solid tumors

A Gras Navarro, AT Björklund, M Chekenya - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are innate lymphoid cells that hold tremendous potential for effective
immunotherapy for a broad range of cancers. Due to the mode of NK cell killing, requiring …

Elevated cancer-specific mortality among HIV-infected patients in the United States

AE Coghill, MS Shiels, G Suneja… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Despite advances in the treatment of HIV, HIV-infected people remain at increased
risk for many cancers, and the number of non–AIDS-defining cancers is increasing with the …

Risk of Merkel cell carcinoma after solid organ transplantation

CA Clarke, HA Robbins, Z Tatalovich… - Journal of the …, 2015 - academic.oup.com
Background: Solid organ transplant recipients have elevated risks of virus-related cancers,
in part because of long-term immunosuppression. Merkel cell carcinoma (MCC) is an …

Kaposi sarcoma–associated herpesvirus-associated malignancies: epidemiology, pathogenesis, and advances in treatment

M Bhutani, MN Polizzotto, TS Uldrick, R Yarchoan - Seminars in oncology, 2015 - Elsevier
Kaposi sarcoma associated herpesvirus (KSHV), a γ2-herpesvirus, also known as human
herpesvirus-8, is the etiologic agent of three virally associated tumors: Kaposi sarcoma, a …

[HTML][HTML] Post-transplant lymphoproliferative disorders: from epidemiology to pathogenesis-driven treatment

MR Petrara, S Giunco, D Serraino, R Dolcetti… - Cancer letters, 2015 - Elsevier
Post-transplant lymphoproliferative disorders (PTLDs) represent the most severe
complication of both solid organ and hematopoietic stem cell transplantation. The Epstein …

[HTML][HTML] HPV carcinomas in immunocompromised patients

NM Reusser, C Downing, J Guidry… - Journal of clinical medicine, 2015 - mdpi.com
Human papillomavirus (HPV) infection is the most common sexually transmitted disease
worldwide and can result in pre-malignancies or overt malignancies of the skin and mucosal …

Immune reconstitution/immunocompetence in recipients of kidney plus hematopoietic stem/facilitating cell transplants

JR Leventhal, MJ Elliott, ES Yolcu, LD Bozulic… - …, 2015 - journals.lww.com
MATERIALS AND METHODS All protocols are approved by the Northwestern University
(NWU) and University of Louisville Institutional Review Boards and the FDA (IDE 13947) …

Combination of ablative fractional laser and daylight‐mediated photodynamic therapy for actinic keratosis in organ transplant recipients–a randomized controlled trial

K Togsverd‐Bo, U Lei, AM Erlendsson… - British Journal of …, 2015 - academic.oup.com
Background Topical photodynamic therapy (PDT) for actinic keratoses (AK) is hampered by
pain during illumination and inferior efficacy in organ‐transplant recipients (OTR). Objectives …

The epidemiology of cancers in human immunodeficiency virus infection and after organ transplantation

AE Grulich, CM Vajdic - Seminars in oncology, 2015 - Elsevier
The authors provide an update on the association between immune deficiency and cancer
risk in people with human immunodeficiency virus (HIV) and in solid organ transplant …