Experience with tranexamic acid, an indirect fibrinolytic inhibitor, started as soon as it was
released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …

Introduction: Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
To date, there are no pharmacologic agents proven to improve outcomes from TBI because …

Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in elective lower
limb arthroplasty surgery. There are potentially even greater physiological benefits in …

Introduction Severely bleeding trauma patients are a small proportion of the major trauma
population but account for 40% of all trauma deaths. Healthcare resource use and costs are …

Trauma is a leading cause of death in both military and civilian populations worldwide.
Although medical advances have improved the overall morbidity and mortality often …

Background The National Institute for Health Research (NIHR) Health Technology
Assessment (HTA) programme supports research tailored to the needs of NHS decision …

Objectives: To review the current evidence for the use of viscoelastic haemostatic assays in
different surgical settings including trauma, cardiac surgery, liver transplantation, as well as …

The optimal resuscitation fluid for uncontrolled bleeding and hemorrhagic shock in both pre-
and in-hospital settings has been an ongoing controversy for decades. Hemorrhage …

Hip and thigh pain are common presentations to the emergency department (ED). Etiologies
range from benign to life threatening, and disposition varies from outpatient follow-up to …

Ингибиторы фибринолиза в терапии аномального маточного кровотечения
пубертатного периода В статье приводится теоретическое и практическое …