Invading viral DNA can be recognized by the host cytosolic DNA sensor, cyclic GMP-AMP
(cGAMP) synthase (cGAS), resulting in production of the second messenger cGAMP, which …

Virus genomes are condensed and packaged inside stable proteinaceous capsids that
serve to protect them during transit from one cell or host organism, to the next. During virus …

As all viruses rely on cellular factors throughout their replication cycle, to be successful they
must evolve strategies to evade and/or manipulate the defence mechanisms employed by …

Herpesviruses are DNA viruses harboring the capacity to establish lifelong latent-recurrent
infections. There is limited knowledge about viruses targeting the innate DNA-sensing …

Epstein-Barr virus (EBV) is etiologically linked to infectious mononucleosis and several
human cancers. EBV encodes a conserved protein kinase BGLF4 that plays a key role in the …

Mesenchymal stem cells (MSCs) are widely used in clinical settings to treat tissue injuries
and autoimmune disorders due to their multipotentiality and immunomodulation. Long-term …

Lymphocyte proliferation, mobility and longevity make them prime targets for virus infection.
Myeloid cells that process and present environmental antigens to lymphocytes are …

Once individuals acquire one of the eight human‐pathogenic herpesviruses, the upcoming
relationship is predefined to last lifelong. Despite the fact that acute phases of herpesviral …

Summary Type I‐interferon (IFN‐I) induction pathway is one of the most commonly
stimulated signaling pathways in response to viral infection. During viral infection this …

Plasmodium falciparum infections have been implicated in immune deficiencies resulting in
ineffective control of E pstein–B arr virus, thereby increasing the risk of endemic B urkitt …