As prevalence of anxiety, posttraumatic stress, and obsessive compulsive disorders
continue to rise worldwide, increasing focus has been placed on immune mediated theories …

Both ageing and chronic stress are associated with altered brain plasticity, dysregulation of
the immune system, and an increased risk of developing brain disorders; all of which have …

Objective To test the hypothesis that anxiety in amnestic mild cognitive impairment (aMCI)
increases rates of conversion to Alzheimer disease (AD) and to identify potential neural …

Anxiety disorders are frequently encountered in the elderly, but they are largely undetected
and untreated. Epidemiological studies indicate a prevalence ranging from 1.2 to 15%. With …

Interactions between biological vulnerability and environmental adversity are central to the
pathophysiology of depression. Given evidence that the hypothalamic-pituitary-adrenal …

Hair cortisol concentrations (HCC) are receiving increased attention as a novel biomarker of
psychophysiological responses to chronic stress, with potential relevance for …

We propose the concept of Cognitive Debt to characterize thoughts and behaviors that
increase vulnerability to symptomatic Alzheimer's disease (AD). Evidence indicates that …

Anxiety disorders are highly prevalent among the elderly and are associated with increased
disability, poor quality of life, and cognitive impairment. Despite this high prevalence and …

Dysregulation of hypothalamus–pituitary–adrenal-activity has been associated with low
back pain (LBP). The underlying mechanisms are not fully explained, but psychological …

The aim of this study was to characterize Carioca High-conditioned Freezing rats (CHF)
regarding their endocrine and metabolic backgrounds. We found an increase in serum …