Cartilage damage in osteoarthritis and rheumatoid arthritis—two unequal siblings
T Pap, A Korb-Pap - Nature Reviews Rheumatology, 2015 - nature.com
Cartilage damage is a key feature of degenerative joint disorders—primarily osteoarthritis
(OA)—and chronic inflammatory joint diseases, such as rheumatoid arthritis (RA) …
(OA)—and chronic inflammatory joint diseases, such as rheumatoid arthritis (RA) …
The role of the synovial fibroblast in rheumatoid arthritis pathogenesis
The role of the synovial fibroblast in rheumatoid arthritis... : Current Opinion in
Rheumatology The role of the synovial fibroblast in rheumatoid arthritis pathogenesis …
Rheumatology The role of the synovial fibroblast in rheumatoid arthritis pathogenesis …
Rheumatoid arthritis, immunosenescence and the hallmarks of aging
P Chalan, A van den Berg, BJ Kroesen… - Current Aging …, 2015 - ingentaconnect.com
Age is the most important risk factor for the development of infectious diseases, cancer and
chronic inflammatory diseases including rheumatoid arthritis (RA). The very act of living …
chronic inflammatory diseases including rheumatoid arthritis (RA). The very act of living …
[HTML][HTML] Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation
Autophagy plays a central role in various disease processes. However, its contribution to
inflammatory arthritides such as rheumatoid arthritis (RA) is unclear. We observed that …
inflammatory arthritides such as rheumatoid arthritis (RA) is unclear. We observed that …
Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box …
Background Rheumatoid arthritis fibroblast-like synovial cells (RA-FLS) show resistance to
methotrexate (MTX) treatment. To better understand the mechanisms of this resistance, RA …
methotrexate (MTX) treatment. To better understand the mechanisms of this resistance, RA …
Manipulating autophagic processes in autoimmune diseases: a special focus on modulating chaperone-mediated autophagy, an emerging therapeutic target
F Wang, S Muller - Frontiers in immunology, 2015 - frontiersin.org
Autophagy, a constitutive intracellular degradation pathway, displays essential role in the
homeostasis of immune cells, antigen processing and presentation, and many other immune …
homeostasis of immune cells, antigen processing and presentation, and many other immune …
TRPC1-mediated Ca2+ entry is essential for the regulation of hypoxia and nutrient depletion-dependent autophagy
Autophagy is a cellular catabolic process needed for the degradation and recycling of
protein aggregates and damaged organelles. Although Ca 2+ is suggested to have an …
protein aggregates and damaged organelles. Although Ca 2+ is suggested to have an …
Protein tyrosine phosphatase nonreceptor type 2: an important regulator of lnterleukin‐6 production in rheumatoid arthritis synovial fibroblasts
B Aradi, M Kato, M Filkova, E Karouzakis… - Arthritis & …, 2015 - Wiley Online Library
Objective To investigate the role of protein tyrosine phosphatase nonreceptor type 2
(PTPN2) in the pathogenesis of rheumatoid arthritis (RA). Methods Synovial tissue samples …
(PTPN2) in the pathogenesis of rheumatoid arthritis (RA). Methods Synovial tissue samples …
Total flavonoids of Bidens bipinnata L. ameliorate experimental adjuvant-induced arthritis through induction of synovial apoptosis
AZ Shen, X Li, W Hu, FH Chen - BMC complementary and alternative …, 2015 - Springer
Background Bidens bipinnata are widely distributed in China, which have been widely used
as a traditional Chinese medicine. The aim of this study was to examine the effect of total …
as a traditional Chinese medicine. The aim of this study was to examine the effect of total …