The expression of 'clock'genes occurs in all tissues, but especially in the suprachiasmatic
nuclei (SCN) of the hypothalamus, groups of neurons in the brain that regulate circadian …

The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

In recent years, relationship between free radicals and oxidative stress with aging, cancer,
atherosclerosis, neurodegenerative disorders, diabetes, and inflammatory diseases became …

Melatonin is a hormone produced by the pineal gland during the night in response to
light/dark information received by the retina and its integration by the suprachiasmatic …

Across invertebrates and vertebrates, steroids are potent signaling molecules that affect
nearly every cell in the organism, including cells of the nervous system. Historically …

Melatonin, a superior antioxidant, is an important molecule which regulates female
reproduction due to its receptor‐mediated and receptor‐independent antioxidant actions. In …

The present study aims to compare 6-sulfatoxymelatonin (aMT6s) secretion patterns and
levels of cortisol and sex hormones (estradiol, progesterone, DHEA, DHEAS, and …

During the non‐breeding season some animals exhibit testicular atrophy, decreased
testicular weight and reduced seminiferous tubule diameter accompanied by depletion of …

Epigenetic mechanisms encode information above and beyond DNA sequence and play a
critical role in brain development and the long-lived effects of environmental cues on the pre …

生物钟现象存在于几乎所有生命体中, 对多种生理活动和生物行为产生影响.
除了中枢神经系统外, 生物钟基因还广泛表达于包括睾丸在内的多种外周组织当中 …