HPV testing as a screen for cervical cancer

A Goodman - Bmj, 2015 - bmj.com
Human papillomavirus (HPV) has been identified as a necessary factor in the development
of pre-invasive and invasive cancers of the lower genital tract, of which cervical cancer is the …

[HTML][HTML] Role of human papillomaviruses in carcinogenesis

R Ghittoni, R Accardi, S Chiocca… - …, 2015 - ncbi.nlm.nih.gov
The human papillomavirus (HPV) family comprises more than 170 different types that
preferentially infect the mucosa of the genitals, upper-respiratory tract, or the skin. The 'high …

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

JA Den Boon, D Pyeon, SS Wang… - Proceedings of the …, 2015 - National Acad Sciences
To study the multistep process of cervical cancer development, we analyzed 128 frozen
cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia …

The clinical impact of using p16INK4a immunochemistry in cervical histopathology and cytology: An update of recent developments

C Bergeron, G Ronco, M Reuschenbach… - … journal of cancer, 2015 - Wiley Online Library
Cervical cancer screening test performance has been hampered by either lack of sensitivity
of Pap cytology or lack of specificity of Human Papillomavirus (HPV) testing. This uncertainty …

Human papillomavirus in the HIV-infected host: epidemiology and pathogenesis in the antiretroviral era

C Brickman, JM Palefsky - Current HIV/AIDS Reports, 2015 - Springer
Human papillomavirus (HPV) infection is associated with essentially all cervical cancers, 80–
90% of anal cancers, and a high proportion of oropharyngeal, vaginal, penile, and vulvar …

Adenocarcinoma of the cervix: should we treat it differently?

NL Williams, TL Werner, EA Jarboe… - Current oncology reports, 2015 - Springer
Worldwide, cervical cancer is a leading cause of mortality among women, causing 265,653
deaths annually. Squamous cell carcinoma (SCC) accounts for 75% of cervical cancer …

Current cervical carcinoma screening guidelines

MJ Schlichte, J Guidry - Journal of clinical medicine, 2015 - mdpi.com
A formidable threat to the health of women, cervical carcinoma can be prevented in many
cases with adequate screening. The current guidelines for cervical carcinoma screening …

[HTML][HTML] Roles of Foxp3 in the occurrence and development of cervical cancer

Q Luo, S Zhang, H Wei, X Pang… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Objective: This study aimed to evaluate the relationship between forkhead box P3 (Foxp3)
expression and clinicopathological characteristics of cervical cancer and to explore the …

Sexually transmitted infections

L Smith, MP Angarone - Urologic Clinics, 2015 - urologic.theclinics.com
STIs encompass a group of infections that can be spread or acquired through sexual
contact. The Centers for Disease Control and Prevention (CDC) estimates approximately 20 …

Comparison of the Roche cobas® 4800 and Digene Hybrid Capture® 2 HPV tests for primary cervical cancer screening in the HPV FOCAL trial

DA Cook, W Mei, LW Smith, DJ van Niekerk… - BMC cancer, 2015 - Springer
Background HPV FOCAL is a randomized trial (ISRCTN79347302, registered 20 Apr 2007)
comparing high-risk (hr) HPV testing vs. liquid-based cytology (LBC) for cervical cancer …