Membrane repair: mechanisms and pathophysiology
ST Cooper, PL McNeil - Physiological reviews, 2015 - journals.physiology.org
Eukaryotic cells have been confronted throughout their evolution with potentially lethal
plasma membrane injuries, including those caused by osmotic stress, by infection from …
plasma membrane injuries, including those caused by osmotic stress, by infection from …
Plasma membrane repair: a central process for maintaining cellular homeostasis
AD Blazek, BJ Paleo, N Weisleder - Physiology, 2015 - journals.physiology.org
Plasma membrane repair is a conserved cellular response mediating active resealing of
membrane disruptions to maintain homeostasis and prevent cell death and progression of …
membrane disruptions to maintain homeostasis and prevent cell death and progression of …
The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle
HP Lo, SJ Nixon, TE Hall, BS Cowling… - Journal of Cell …, 2015 - rupress.org
Dysfunction of caveolae is involved in human muscle disease, although the underlying
molecular mechanisms remain unclear. In this paper, we have functionally characterized …
molecular mechanisms remain unclear. In this paper, we have functionally characterized …
MG53-mediated cell membrane repair protects against acute kidney injury
Injury to the renal proximal tubular epithelium (PTE) represents the underlying consequence
of acute kidney injury (AKI) after exposure to various stressors, including nephrotoxins and …
of acute kidney injury (AKI) after exposure to various stressors, including nephrotoxins and …
Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury
Ischemic heart disease is a leading cause of death in human population and protection of
myocardial infarction (MI) associated with ischemia–reperfusion (I/R) remains a challenge …
myocardial infarction (MI) associated with ischemia–reperfusion (I/R) remains a challenge …
Cavin family: new players in the biology of caveolae
Caveolae are specialized small plasma-membrane invaginations that play crucial cellular
functions. Two essential protein families are required for caveola formation: membrane …
functions. Two essential protein families are required for caveola formation: membrane …
Effect of metabolic syndrome on mitsugumin 53 expression and function
Metabolic syndrome is a cluster of risk factors, such as obesity, insulin resistance, and
hyperlipidemia that increases the individual's likelihood of developing cardiovascular …
hyperlipidemia that increases the individual's likelihood of developing cardiovascular …
Zinc binding to MG53 protein facilitates repair of injury to cell membranes
Zinc is an essential trace element that participates in a wide range of biological functions,
including wound healing. Although Zn 2+ deficiency has been linked to compromised …
including wound healing. Although Zn 2+ deficiency has been linked to compromised …
[HTML][HTML] Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is a childhood soft tissue tumor with broad expression of
markers that are typically found in skeletal muscle. Cavin-1 is a recently discovered protein …
markers that are typically found in skeletal muscle. Cavin-1 is a recently discovered protein …
Different pathways to the lysosome: sorting out alternatives
M Hasanagic, A Waheed, JC Eissenberg - International review of cell and …, 2015 - Elsevier
Considerable research supports a model in which hydrolytic enzymes of mammalian
lysosomes are sorted to their destinations in a receptor-dependent mechanism. The ligand …
lysosomes are sorted to their destinations in a receptor-dependent mechanism. The ligand …