Scavenger receptors: emerging roles in cancer biology and immunology
Scavenger receptors constitute a large family of evolutionally conserved protein molecules
that are structurally and functionally diverse. Although scavenger receptors were originally …
that are structurally and functionally diverse. Although scavenger receptors were originally …
Rho regulation: DLC proteins in space and time
AC Braun, MA Olayioye - Cellular signalling, 2015 - Elsevier
Rho GTPases function as molecular switches that connect changes of the external
environment to intracellular signaling pathways. They are active at various subcellular sites …
environment to intracellular signaling pathways. They are active at various subcellular sites …
Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes
Aims: Nasopharyngeal carcinoma (NPC) is a common tumor consistently associated with
Epstein–Barr virus infection and prevalent in South China, including Hong Kong, and …
Epstein–Barr virus infection and prevalent in South China, including Hong Kong, and …
Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer
K Torabi, R Miró, N Fernández-Jiménez… - …, 2015 - academic.oup.com
Colorectal cancer (CRC) is characterized by specific patterns of copy number alterations
(CNAs), which helped with the identification of driver oncogenes and tumor suppressor …
(CNAs), which helped with the identification of driver oncogenes and tumor suppressor …
Low expression of DLC1 is predictive of poor therapeutic efficiency of fluoropyrimidine and oxaliplatin as adjuvant chemotherapy in gastric cancer
Y Su, L Lin, J Zhang, Y Jiang… - Molecular …, 2015 - spandidos-publications.com
Abstract The Rho‑GTPase‑activating protein, deleted in liver cancer‑1 (DLC1), has been
reported to be a tumor suppressor. However, the prognostic value of DLC1 in gastric cancer …
reported to be a tumor suppressor. However, the prognostic value of DLC1 in gastric cancer …
Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma
CR Xie, HG Sun, Y Sun, WX Zhao… - Molecular …, 2015 - spandidos-publications.com
DLC1 has been shown to be downregulated or absent in hepatocellular carcinoma (HCC)
and is associated with tumorigenesis and development. However, only a small number of …
and is associated with tumorigenesis and development. However, only a small number of …
[HTML][HTML] Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells
C Mao, H Liu, P Chen, J Ye, L Teng, Z Jia, J Cao - Oncotarget, 2015 - ncbi.nlm.nih.gov
To achieve specific and potent antitumor effect of hepatocyte carcinoma cells, replication
defective adenoviral vectors, namely rAd/AFP-amiRG, rAd/AFP-amiRE and rAd/AFP-amiRP …
defective adenoviral vectors, namely rAd/AFP-amiRG, rAd/AFP-amiRE and rAd/AFP-amiRP …
Quantitative proteomic analysis and gene expression profiling microarray re-analysis of uveal melanoma
P Ramasamy - 2015 - repository.rcsi.com
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults and
40% develop fatal metastatic disease. Compared to tumours with chromosome 3 disomy …
40% develop fatal metastatic disease. Compared to tumours with chromosome 3 disomy …
The Effects of 5-Aza-2-Deoxycytidine on DLC-1 Gene Expression, Methylation Level and Expression of Downstream Signaling Molecules Cdc42 in Multiple Myeloma
X Feng, L Zhang, S Nie, Z Su, X Shi… - Current Signal …, 2015 - ingentaconnect.com
Objective: To investigate the effects of the DNA methyltransferase inhibitor 5-Aza-2'-
Deoxycytidine (5-Aza-Dc) on DLC-1 gene expression, methylation level, and the expression …
Deoxycytidine (5-Aza-Dc) on DLC-1 gene expression, methylation level, and the expression …