Objective P-selectin is a cellular adhesion molecule that has been shown to be crucial in
development of coronary heart disease (CHD). We sought to determine the role of P-selectin …

Inclacumab, a novel monoclonal antibody against P-selectin in development for the
treatment and prevention of atherosclerotic cardiovascular diseases, was administered in an …

Background/aim Recent studies have emphasized the importance of the inflammatory
response mediated by monocyte and neutrophil activation in deep venous thrombosis …

Objectives In the present study, we establish two swine models of iliac vein occlusion (IVO)
with spontaneous thrombosis to understand the mechanisms linking IVO and thrombosis …

1. Background Venous thromboembolism (VTE), the collective term for deep vein thrombosis
(DVT) and pulmonary embolism (PE), is a major contributor to the global burden of disease …

Øystein Bruserud a, b,⁎, Håkon Reikvam a, b, ca Department of Clinical Science, Section of
Hematology, University of Bergen, Bergen, Norway b Department of Medicine, Section for …

En primer lugar quiero mostrar mi mayor agradecimiento a mis directores de Tesis. A la Dra.
Mª José García-Fuster, por su motivación para la realización de este proyecto, por su …

Background Venous thromboembolism (VTE) is an umbrella term for the pathological
development of blood clots in the venous system. These include pulmonary embolism (PE) …