A variety of fatty acids exists in the diet of humans, in the bloodstream of humans, and in
cells and tissues of humans. Fatty acids are energy sources and membrane constituents …

Inflammation is a condition which contributes to a range of human diseases. It involves a
multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) …

Skeletal and cardiac muscles play key roles in the regulation of systemic energy
homeostasis and display remarkable plasticity in their metabolic responses to caloric …

The peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated
transcriptional factor that belongs to the nuclear hormone receptor superfamily. PPARγ was …

Nuclear receptors are ligand-activated transcription factors, which represent a primary class
of drug targets. The nuclear receptor peroxisome proliferator-activated receptor gamma …

The ultrastructure of the cardiac myocyte is remarkable for the high density of mitochondria
tightly packed between sarcomeres. This structural organization is designed to provide …

We investigate crosstalk between cancer cells and stromal myeloid cells. We find that Lewis
lung carcinoma cells significantly induce PPARβ/δ activity in myeloid cells in vitro and in …

Lipid droplets exist in virtually every cell type, ranging not only from mammals to plants, but
also to eukaryotic and prokaryotic unicellular organisms such as D ictyostelium and bacteria …

Overwhelming consensus emerges among countless evidences that obesity is
characterized by a chronic low‐grade inflammation in the adipose tissue (AT), which …

Lipids play vital roles in a wide variety of cellular functions. They act as structural
components in cell membranes, serve as a major form of energy storage, and function as …