[HTML][HTML] Development of targeted therapies in treatment of glioblastoma
YY Xu, P Gao, Y Sun, YR Duan - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is a type of tumor that is highly lethal despite maximal therapy.
Standard therapeutic approaches provide modest improvement in progression-free and …
Standard therapeutic approaches provide modest improvement in progression-free and …
Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and in vivo studies in drug delivery
Over the past few decades, cell penetrating peptides (CPPs) have become an important
class of drug carriers for small molecules, proteins, genes and nanoparticle systems. CPPs …
class of drug carriers for small molecules, proteins, genes and nanoparticle systems. CPPs …
Systemic delivery of blood–brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue
Delivery of therapeutic agents to the central nervous system is a significant challenge,
hindering progress in the treatment of diseases such as glioblastoma. Due to the presence …
hindering progress in the treatment of diseases such as glioblastoma. Due to the presence …
CREKA peptide-conjugated dendrimer nanoparticles for glioblastoma multiforme delivery
J Zhao, B Zhang, S Shen, J Chen, Q Zhang… - Journal of colloid and …, 2015 - Elsevier
Glioblastoma multiforme (GBM) is the most aggressive central nervous system (CNS) tumor
because of its fast development, poor prognosis, difficult control and terrible mortality. Poor …
because of its fast development, poor prognosis, difficult control and terrible mortality. Poor …
Investigation of enzyme-sensitive lipid nanoparticles for delivery of siRNA to blood–brain barrier and glioma cells
Clinical applications of siRNA for treating disorders in the central nervous system require
development of systemic stable, safe, and effective delivery vehicles that are able to cross …
development of systemic stable, safe, and effective delivery vehicles that are able to cross …
Lipid Bilayer Crossing The Gate of Symmetry. Water-Soluble Phenylproline-Based Blood-Brain Barrier Shuttles
P Arranz-Gibert, B Guixer… - Journal of the …, 2015 - ACS Publications
Drug delivery to the brain can be achieved by various means, including blood-brain barrier
(BBB) disruption, neurosurgical-based approaches, and molecular design. Recently …
(BBB) disruption, neurosurgical-based approaches, and molecular design. Recently …
[HTML][HTML] Paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulation
W Li, Z Qi, Z Wei, S Liu, P Wang… - Molecular …, 2015 - spandidos-publications.com
Paeoniflorin is one of the active ingredients of the commonly used herbal medicine derived
from Paeonia, which exhibits anticancer properties. MicroRNA‑16 (miR‑16) is upregulated in …
from Paeonia, which exhibits anticancer properties. MicroRNA‑16 (miR‑16) is upregulated in …
Taming cell penetrating peptides: never too old to teach old dogs new tricks
Cell penetrating peptides (CPPs) have received substantial attention due to their intrinsic
property to cross plasma membranes or even as helpers to facilitate the cellular entry of drug …
property to cross plasma membranes or even as helpers to facilitate the cellular entry of drug …
Emerging antitumor applications of extracellularly reengineered polymeric nanocarriers
Recently, polymeric nanocarriers with shielding surfaces, eg, poly (ethylene glycol) and
small molecules, have been widely applied in antitumor drug delivery mainly because of …
small molecules, have been widely applied in antitumor drug delivery mainly because of …
Nanomedicines and stroke: Toward translational research
Since their introduction in the late 60′, nanotechnologies applied to medicine, called
nanomedicines, are believed to have the potential to be the mankind's first “giant step” …
nanomedicines, are believed to have the potential to be the mankind's first “giant step” …