Adrenocortical carcinoma (ACC): diagnosis, prognosis, and treatment

R Libé - Frontiers in cell and developmental biology, 2015 - frontiersin.org
Adrenocortical carticnoma (ACC) is a rare malignancy with an incidence of 0.7–2.0
cases/million habitants/year. The diagnosis of malignancy relies on careful investigations of …

Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study

M Fassnacht, A Berruti, E Baudin, MJ Demeure… - The lancet …, 2015 - thelancet.com
Background Adrenocortical carcinoma is a rare, aggressive cancer for which few treatment
options are available. Linsitinib (OSI-906) is a potent, oral small molecule inhibitor of both …

[HTML][HTML] Prognostic factors in stage III–IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study

R Libe, I Borget, CL Ronchi, B Zaggia, M Kroiss… - Annals of …, 2015 - Elsevier
Background The clinical course of advanced adrenocortical carcinoma (ACC) is
heterogeneous. Our study aimed primarily to refine and make headway in the prognostic …

Adrenocortical carcinoma

E Baudin - Endocrinology and Metabolism Clinics, 2015 - endo.theclinics.com
Adrenocortical carcinoma (ACC) originates from the adrenal cortex and is typically defined
by positive immunostaining for steroidogenic factor 1 (SF1), melanA (Mart1) markers but …

Programmed death ligand-1 expression in adrenocortical carcinoma: an exploratory biomarker study

AP Fay, S Signoretti, M Callea, GH Telό… - … for immunotherapy of …, 2015 - Springer
Background Adrenocortical carcinoma (ACC) is a rare tumor in which prognostic factors are
still not well established. Programmed Death Ligand-1 (PD-L1) expression in ACC and its …

Adjuvant radiation therapy improves local control after surgical resection in patients with localized adrenocortical carcinoma

A Sabolch, T Else, KA Griffith, E Ben-Josef… - International Journal of …, 2015 - Elsevier
Purpose Adrenocortical carcinoma (ACC) is a rare malignancy known for high rates of local
recurrence, though the benefit of postoperative radiation therapy (RT) has not been …

Diagnosis, treatment and outcome of adrenocortical cancer

R Mihai - Journal of British Surgery, 2015 - academic.oup.com
Background Adrenocortical cancer (ACC) is a rare disease with a dismal prognosis. The
majority of patients are diagnosed with advanced disease and raise difficult management …

Computed tomography criteria for discrimination of adrenal adenomas and adrenocortical carcinomas: analysis of the German ACC registry

S Petersenn, PA Richter, T Broemel… - European journal of …, 2015 - academic.oup.com
Objective Thresholds of 2–20 hounsfield units (HU) in unenhanced computed tomography
(CT) are suggested to discriminate benign adrenal tumors (BATs) from malignant adrenal …

Diagnostic and prognostic features in adrenocortical carcinoma: a single institution case series and review of the literature

KN Wanis, R Kanthan - World Journal of Surgical Oncology, 2015 - Springer
Background Adrenocortical carcinoma is a rare cancer, with an incidence in the literature of
0.5 to 2 cases per million population per year. Adult adrenocortical carcinoma has a poor …

Surgical resection of synchronously metastatic adrenocortical cancer

BM Dy, V Strajina, AK Cayo, ML Richards… - Annals of surgical …, 2015 - Springer
Introduction Metastatic adrenocortical carcinoma (ACC) is rapidly fatal, with few options for
treatment. Patients with metachronous recurrence may benefit from surgical resection. The …