Background A recombinant, replication-competent vesicular stomatitis virus-based vaccine
expressing a surface glycoprotein of Zaire Ebolavirus (rVSV-ZEBOV) is a promising Ebola …

The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a
licensed drug or vaccine to combat the disease and has renewed the urgency to develop a …

The latest Ebola virus (EBOV) epidemic spread rapidly through Guinea, Sierra Leone, and
Liberia, creating a global public health crisis and accelerating the assessment of …

Background Safe and effective vaccines against Ebola could prevent or control outbreaks.
The safe use of replication-competent vaccines requires a careful dose-selection process …

Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans.
As a major impediment to vaccine development, delayed and weak neutralizing antibody …

The filoviruses, Ebola virus and Marburg virus, are zoonotic pathogens that cause severe
hemorrhagic fever in humans and nonhuman primates (NHPs), with case-fatality rates …

The family Filoviridae contains several of the most deadly pathogens known to date and the
current Ebola virus disease (EVD) outbreak in Western Africa, due to Ebola virus (EBOV) …

Background. We report the first-in-human safety and immunogenicity evaluation of a highly
attenuated, replication-competent recombinant vesicular stomatitis virus (rVSV) human …

We previously described the generation of a novel Ebola virus (EBOV) vaccine based on
inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) incorporated in the …

An international collaborative study was conducted to establish the 1 st WHO International
Standard for use in the standardisation of Polyoma virus BKV nucleic acid amplification …