Lower respiratory tract infections frequently complicate stroke and adversely affect outcome.
There is currently no agreed terminology or gold-standard diagnostic criteria for the …

Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Neutrophils are rapidly recruited in response to local tissue infection or inflammation. Stroke
triggers a strong inflammatory reaction but the relevance of neutrophils in the ischemic brain …

Background In adults with acute stroke, infections occur commonly and are associated with
an unfavourable functional outcome. In the Preventive Antibiotics in Stroke Study (PASS) we …

Acute brain lesions induce profound alterations of the peripheral immune response
comprising the opposing phenomena of early immune activation and subsequent …

Background—Inflammatory and immune responses triggered by brain ischemia worsen
clinical outcomes of stroke and contribute to hemorrhagic transformation, massive edema …

Numerous treatments have been reported to provide a beneficial outcome in experimental
animal stroke models; however, these treatments (with the exception of tissue plasminogen …

Despite their delayed recruitment in the brain, Treg have been found, in both depletion and
therapeutic paradigms (see below), to influence stroke outcomes within the first days after …

Stroke is the fourth leading cause of death in the United States and the second most
common cause of death worldwide; stroke is also the leading cause of long-term disability …

Major pulmonary disorders may occur after brain injuries as ventilator-associated
pneumonia, acute respiratory distress syndrome or neurogenic pulmonary edema. They are …