Covering: up to 2015 In recent years, bacterial interspecies interactions mediated by small
molecule natural products have been found to give rise to a surprising array of phenotypes …

Despite recent advancements in the diagnosis and management of fungal infections [1],
invasive fungal diseases remain a major cause of morbidity and mortality in …

Iron is essential in many biological processes. However, its bioavailability is reduced in
aerobic environments, such as soil. To overcome this limitation, microorganisms have …

Abstract Background Next Generation DNA Sequencing (NGS) and genome mining of
actinomycetes and other microorganisms is currently one of the most promising strategies …

N-Hydroxylating monooxygenases are involved in the biosynthesis of iron-chelating
hydroxamate-containing siderophores that play a role in microbial virulence. These …

A new siderophore named albachelin was isolated from iron deficient culture of
Amycolatopsis alba. The planar structure of albachelin was elucidated by the combination of …

A metal-templated synthesis (MTS) approach was used to preorganize the forward endo-
hydroxamic acid monomer 4-[(5-aminopentyl)(hydroxy) amino]-4-oxobutanoic acid (for-PBH) …

Natural products, which result from secondary or specialized metabolism, have provided
with molecules to human welfare for millennia. However, decline of chemical discovery pace …

Historically microbial natural product biosynthesis pathways were elucidated mainly by
isotope labelled precursor directed feeding studies. Now the genetics underpinning the …

目的鉴定从始旋链霉菌中发现的诺卡胺类物质. 方法利用超高效液相色谱-质谱联用(UPLC-MS)
技术, 结合二级质谱解析, 数据库检索等多种手段分析和鉴定始旋链霉菌HCCB 10218 …