A method of measuring cortical oxygen metabolism in the mouse brain that uses
independent quantitative measurements of three key parameters: cerebral blood flow (CBF) …

In order to protect the brain before an irreversible injury occurs, penumbral oxygenation is
the primary goal of current acute ischemic stroke treatment. However, hyperoxia treatment …

The cerebral microvessels are parenchymal branches of the brain's penetrating vessels that
include small diameter arterioles and capillaries and through which the cerebral …

Abstract Background Laser Doppler flowmetry (LDF) is widely used for estimating cerebral
blood flow changes during intraluminal middle cerebral artery occlusion (MCAO). No …

Deep brain stimulation (DBS) is a therapeutic intervention used for a variety of neurological
and psychiatric disorders, but its mechanism of action is not well understood. It is known that …

Stroke is a major cause of death and disability worldwide. However, treatment options to
date are very limited. To meet the need for validating the novel therapeutic approaches and …

Rodent middle cerebral artery occlusion (MCAO) model is commonly used in stroke
research. Creating a stable infarct volume has always been challenging for technicians due …

Cerebral blood flow (CBF) plays a critical role in the exchange of nutrients and metabolites
at the capillary level and is tightly regulated to meet the metabolic demands of the brain …

A neuroimaging technique based on the saturation-recovery (SR)-T1 MRI method was
applied for simultaneously imaging blood oxygenation level dependence (BOLD) contrast …

Cerebral collateral circulation is a subsidiary vascular network which is dynamically
recruited after acute ischemic stroke and may provide residual blood flow to the affected …