Anticancer effect of antimalarial artemisinin compounds
AK Das - Annals of medical and health sciences research, 2015 - ajol.info
The anti‑malarial drug artemisinin has shown anticancer activity in vitro and animal
experiments, but experience in human cancer is scarce. However, the ability of artemisinins …
experiments, but experience in human cancer is scarce. However, the ability of artemisinins …
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux
S Giuliano, Y Cormerais, M Dufies, R Grépin… - Autophagy, 2015 - Taylor & Francis
Metastatic renal cell carcinomas (mRCC) are highly vascularized tumors that are a paradigm
for the treatment with antiangiogenesis drugs targeting the vascular endothelial growth …
for the treatment with antiangiogenesis drugs targeting the vascular endothelial growth …
Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells
A Grimaldi, D Santini, S Zappavigna… - Cancer biology & …, 2015 - Taylor & Francis
Renal cell carcinoma is an aggressive disease often asymptomatic and weakly chemo-
radiosensitive. Currently, new biologic drugs are used among which everolimus, an mTOR …
radiosensitive. Currently, new biologic drugs are used among which everolimus, an mTOR …
Design, Synthesis and In Vitro Antiproliferative Activity of Novel Isatin‐Quinazoline Hybrids
Using a molecular hybridization approach, a new series of isatin‐quinazoline hybrids 15a–o
was designed and synthesized via two different synthetic routes. The target compounds 15a …
was designed and synthesized via two different synthetic routes. The target compounds 15a …
[HTML][HTML] The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells
C Simioni, A Cani, AM Martelli, G Zauli, AAM Alameen… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common lethal human malignancies
worldwide and its advanced status is frequently resistant to conventional chemotherapeutic …
worldwide and its advanced status is frequently resistant to conventional chemotherapeutic …
液相质谱串联法同时测定舒尼替尼及其活性代谢产物SU12662 在BABL/c 裸鼠血浆中的浓度及其药物动力学研究
李静云， 李健， 王思媛， 袁茵， 苏青虹， 卢炜… - 中国药学(英文版 …, 2015 - jcps.bjmu.edu.cn
本研究建立并验证了一种灵敏, 快速, 简单的液质联用方法, 用于同时测定BABL/c
裸鼠血浆中舒尼替尼及其活性代谢产物SU12662 的药物浓度. 血浆样品采用蛋白沉淀方法处理 …
裸鼠血浆中舒尼替尼及其活性代谢产物SU12662 的药物浓度. 血浆样品采用蛋白沉淀方法处理 …
[PDF][PDF] The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells
JA McCubrey - 2015 - thescholarship.ecu.edu
Hepatocellular carcinoma (HCC) is one of the most common lethal human malignancies
worldwide and its advanced status is frequently resistant to conventional chemotherapeutic …
worldwide and its advanced status is frequently resistant to conventional chemotherapeutic …