Since the first heart transplantation (HT) in 1967, survival has steadily improved. Issues
related to over-and under-immunosuppression are, however, still common following HT …

Heart transplantation is currently the definitive gold standard surgical approach in the
treatment of refractory heart failure. However, the shortage of donors limits the achievement …

The primary cause of mortality at 5 years following a cardiac transplantation is the
development of atherosclerosis, termed coronary allograft vasculopathy (CAV). This …

Although coronary angiography is currently the imaging technique of choice for screening
and diagnosing CAV, 3 it lacks sensitivity when compared with IVUS, 14, 15 OCT, and …

Background Although acute cellular rejection after heart transplantation (HTX) can be
controlled by full-dose calcineurin inhibitor (CNI)–based immunosuppressive regimens …

Cardiac allograft vasculopathy (CAV) is a common complication following heart
transplantation (HT), resulting in diminished graft survival. The preferred strategy for …

Heart transplantation is currently the definitive gold standard surgical approach in the
treatment of refractory heart failure. However, the shortage of donors limits the achievement …

Heart transplantation remains the most durable treatment for end-stage heart disease that is
not amenable to coronary revascularization or anti-arrhythmic therapies. Cardiac allograft …

The prevalence of heart failure continues to rise due to the aging population and longer
survival of people with conditions that lead to heart failure, eg, hypertension, diabetes, and …

Background Immune monitoring (IM) has not been shown to be associated with cardiac
allograft vasculopathy (CAV). Methods Maximal intimal area, average percent stenosis …