Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

BFJ Verhaaren, S Debette, JC Bis… - Circulation …, 2015 - Am Heart Assoc
Background—The burden of cerebral white matter hyperintensities (WMH) is associated with
an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic …

[HTML][HTML] Markers of cardiac dysfunction in cognitive impairment and dementia

S Hilal, YL Chai, MK Ikram, S Elangovan, TB Yeow… - Medicine, 2015 - journals.lww.com
Markers of cardiac dysfunction such as amino terminal pro-brain natriuretic peptide (NTpro-
BNP) and high sensitivity cardiac troponin T (hs-cTnT) may be associated with dementia …

[HTML][HTML] A priori collaboration in population imaging: the Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium

HHH Adams, S Hilal, P Schwingenschuh… - Alzheimer's & Dementia …, 2015 - Elsevier
Abstract Introduction Virchow-Robin spaces (VRS), or perivascular spaces, are
compartments of interstitial fluid enclosing cerebral blood vessels and are potential imaging …

Subcortical atrophy in cognitive impairment and dementia

S Hilal, SM Amin… - Journal of …, 2015 - content.iospress.com
Background: Cortical atrophy is a key neuroimaging feature of dementia. However, the role
of subcortical gray matter reduction in cognitive impairment has not been explored …

Intracranial stenosis, cerebrovascular diseases, and cognitive impairment in Chinese

S Hilal, M Saini, CS Tan, JA Catindig… - Alzheimer Disease & …, 2015 - journals.lww.com
Extracranial carotid artery disease has been shown to be related to cognitive deficits.
However, limited data are available on intracranial stenosis (ICS) and cognitive impairment …

[HTML][HTML] Improved predictive ability of the Montreal Cognitive Assessment for diagnosing dementia in a community-based study

JL Hsu, YC Fan, YL Huang, J Wang, WH Chen… - Alzheimer's research & …, 2015 - Springer
Introduction We compared the predictive ability of the Mini-Mental State Examination
(MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a …

Chromosomal DNA damage measured using the cytokinesis‐block micronucleus cytome assay is significantly associated with cognitive impairment in S outh A …

SL Lee, P Thomas, J Hecker, J Faunt… - Environmental and …, 2015 - Wiley Online Library
Loss of genome integrity may be associated with increased risk for neurodegenerative
disease. The aim of this study was to investigate whether mild cognitive impairment (MCI) or …

Prevalence and risk factors of acute incidental infarcts

M Saini, MSP Suministrado, S Hilal, YH Dong… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The study of silent stroke has been limited to imaging of chronic
infarcts; acute incidental infarcts (AII) detected on brain magnetic resonance imaging have …

[HTML][HTML] Risk factors and consequences of cortical thickness in an Asian population

S Hilal, X Xin, SL Ang, CS Tan… - Medicine, 2015 - journals.lww.com
Risk Factors and Consequences of Cortical Thickness in an As... : Medicine Risk Factors
and Consequences of Cortical Thickness in an Asian Population : Medicine Log in or …

Association of neuropsychiatric symptoms and sub-syndromes with cognitive impairment in community-dwelling Asian elderly

X Xu, SL Ang, S Hilal, QL Chan, TY Wong… - International …, 2015 - cambridge.org
Objectives: To investigate the presence of neuropsychiatric symptoms (NPS) and sub-
syndromes in elderly community-dwelling Asians with varying severity of cognitive …