Focused ion beams in biology

K Narayan, S Subramaniam - Nature methods, 2015 - nature.com
A quiet revolution is under way in technologies used for nanoscale cellular imaging.
Focused ion beams, previously restricted to the materials sciences and semiconductor …

Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview

SR Saptarshi, A Duschl, AL Lopata - Nanomedicine, 2015 - Taylor & Francis
Zinc oxide nanoparticles (ZnO NPs) have useful physicochemical advantages, and are used
extensively. This has raised concerns regarding their potential toxicity. ZnO NP attributes …

Acute exposure to ZnO nanoparticles induces autophagic immune cell death

BM Johnson, JA Fraietta, DT Gracias, JL Hope… - …, 2015 - Taylor & Francis
The increasing risk of incidental exposure to nanomaterials has led to mounting concerns
regarding nanotoxicity. Zinc oxide nanoparticles (ZnO NPs) are produced in large quantities …

Reducing the cytotoxicity of ZnO nanoparticles by a pre-formed protein corona in a supplemented cell culture medium

H Yin, R Chen, PS Casey, PC Ke, TP Davis, C Chen - Rsc Advances, 2015 - pubs.rsc.org
The safety of zinc oxide (ZnO) nanoparticles (NPs) remains a critical concern considering
that they are a common constituent in cosmetics and sunscreen formulation. In our study, the …

[HTML][HTML] Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo

SR Saptarshi, BN Feltis, PFA Wright… - Journal of …, 2015 - Springer
Background This study evaluates the time-dependent pro-inflammatory response of the
model human lung epithelial cells (A549) to industrially relevant zinc oxide nanoparticles …

A review of critical factors for assessing the dermal absorption of metal oxide nanoparticles from sunscreens applied to humans, and a research strategy to address …

B Gulson, MJ McCall, DM Bowman, T Pinheiro - Archives of toxicology, 2015 - Springer
Metal oxide nanoparticles in sunscreens provide broad-spectrum ultraviolet protection to
skin. All studies to assess dermal penetration of nanoparticles have unanimously concluded …

[HTML][HTML] Novel ZnO: Ag nanocomposites induce significant oxidative stress in human fibroblast malignant melanoma (Ht144) cells

S Arooj, S Nazir, A Nadhman, N Ahmad… - Beilstein journal of …, 2015 - beilstein-journals.org
The use of photoactive nanoparticles (NPs) such as zinc oxide (ZnO) and its
nanocomposites has become a promising anticancer strategy. However, ZnO has a low …

Size‐dependent cytotoxicity and genotoxicity of Z n O particles to human lymphoblastoid (WIL 2‐NS) cells

H Yin, PS Casey, MJ McCall… - Environmental and …, 2015 - Wiley Online Library
The relationship between particle size and cytogenotoxicity of ZnO particles was
systematically studied in vitro using WIL2‐NS human lymphoblastoid cells. Before toxicity …

Considerations of inductively coupled plasma mass spectrometry techniques for characterizing the dissolution of metal-based nanomaterials in biological tissues

CK Su, YC Sun - Journal of Analytical Atomic Spectrometry, 2015 - pubs.rsc.org
Dissolution of metal-based nanomaterials (MNMs) leads to the release of metal ion species;
this phenomenon is a major concern affecting the widespread application of MNMs because …

Multidimensional characterisation of biomechanical structures by combining Atomic Force Microscopy and Focused Ion Beam: A study of the rat whisker

VR Adineh, B Liu, R Rajan, W Yan, J Fu - Acta biomaterialia, 2015 - Elsevier
Understanding the heterogeneity of biological structures, particularly at the micro/nano scale
can offer insights valuable for multidisciplinary research in tissue engineering and …