Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain
tumors. The synuclein family consists of three members: α-, β-, and γ-synucleins present …

The capacity of endogenous Tau to bind DNA has been recently identified in neurons under
physiological or oxidative stress conditions. Characterization of the protein domains …

Parkinson's disease (PD) is one of the most prevalent movement disorders in the world. A
clinical hallmark of PD is the appearance of proteinaceous Lewy Bodies throughout the …

Amyloidoses are a group of protein misfolding disorders which are characterised by the
abnormal accumulation of highly ordered filamentous assemblies, known as amyloid fibrils …

[eng] Single-molecule techniques allow to following biomolecular reactions with
unprecedented resolution. Particularly, optical tweezers can be used to manipulate and …

The accumulation of microtubule-associated protein tau into fibrillar aggregates is the
hallmark of Alzheimer's disease and other neurodegenerative disorders, collectively referred …