Recent advances in organocatalytic cascade reactions toward the formation of quaternary stereocenters
This review provides the authors' selection of recent publications that highlight the
increasing efforts to develop valuable organocatalytic domino/tandem/cascade reactions as …
increasing efforts to develop valuable organocatalytic domino/tandem/cascade reactions as …
Asymmetric Brønsted acid catalyzed synthesis of triarylmethanes—construction of communesin and spiroindoline scaffolds
HH Liao, A Chatupheeraphat, CC Hsiao… - Angewandte Chemie …, 2015 - Wiley Online Library
Aza‐ortho‐quinone methides allow the straightforward asymmetric synthesis of natural‐
product‐inspired indole scaffolds possessing a quaternary stereocenter. Our approach …
product‐inspired indole scaffolds possessing a quaternary stereocenter. Our approach …
Progress toward the development of noscapine and derivatives as anticancer agents
Many nitrogen-moiety containing alkaloids derived from plant origins are bioactive and play
a significant role in human health and emerging medicine. Noscapine, a …
a significant role in human health and emerging medicine. Noscapine, a …
Biology‐Oriented Synthesis of a Withanolide‐Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling
J Švenda, M Sheremet, L Kremer, L Maier… - Angewandte …, 2015 - Wiley Online Library
Biology‐oriented synthesis employs the structural information encoded in complex natural
products to guide the synthesis of compound collections enriched in bioactivity. The trans …
products to guide the synthesis of compound collections enriched in bioactivity. The trans …
De novo branching cascades for structural and functional diversity in small molecules
M Garcia-Castro, L Kremer, CD Reinkemeier… - Nature …, 2015 - nature.com
The limited structural diversity that a compound library represents severely restrains the
discovery of bioactive small molecules for medicinal chemistry and chemical biology …
discovery of bioactive small molecules for medicinal chemistry and chemical biology …
Highly Stereoselective Synthesis of Natural‐Product‐Like Hybrids by an Organocatalytic/Multicomponent Reaction Sequence
R Echemendía, AF de La Torre… - Angewandte Chemie …, 2015 - Wiley Online Library
In an endeavor to provide an efficient route to natural product hybrids, described herein is an
efficient, highly stereoselective, one‐pot process comprising an organocatalytic conjugate …
efficient, highly stereoselective, one‐pot process comprising an organocatalytic conjugate …
Highly Enantioselective Intramolecular 1, 3‐Dipolar Cycloaddition: A Route to Piperidino‐Pyrrolizidines
SR Vidadala, C Golz, C Strohmann… - Angewandte …, 2015 - Wiley Online Library
Abstract Enantioselective catalytic intermolecular 1, 3‐dipolar cycloadditions are powerful
methods for the synthesis of heterocycles. In contrast, intramolecular enantioselective 1, 3 …
methods for the synthesis of heterocycles. In contrast, intramolecular enantioselective 1, 3 …
Total synthesis of steroids and heterosteroids from BISTRO
M Ibrahim-Ouali - Steroids, 2015 - Elsevier
Total synthesis of steroids and heterosteroids from BISTRO - ScienceDirect Skip to main
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Asymmetrische Brønsted‐Säure‐katalysierte Synthese von Triarylmethanen–Aufbau von Communesin‐und Spiroindolin‐Gerüsten
HH Liao, A Chatupheeraphat, CC Hsiao… - Angewandte …, 2015 - Wiley Online Library
Aza‐ortho‐Chinonmethide ermöglichen eine effiziente asymmetrische Synthese Naturstoff‐
inspirierter Indolgerüste mit quartärem Stereozentrum. Mit diesem Ansatz konnten diverse …
inspirierter Indolgerüste mit quartärem Stereozentrum. Mit diesem Ansatz konnten diverse …
A general catalytic reaction sequence to access alkaloid-inspired indole polycycles
A Danda, K Kumar, H Waldmann - Chemical Communications, 2015 - pubs.rsc.org
A catalytic two-step reaction sequence was developed to access a range of complex
heterocyclic frameworks based on biorelevant indole/oxindole scaffolds. The reaction …
heterocyclic frameworks based on biorelevant indole/oxindole scaffolds. The reaction …