Rosuvastatin is a fully synthetic statin wich acts by interfering with the endogenous synthesis
of cholesterol through competitively inhibiting the 3-hydroxy-3-methylglutaryl coenzyme A …

Solid organ transplantation has become the standard of care for patients with endstage liver,
kidney, lung, and heart diseases and has significantly improved the survival and quality of …

Organic anion transporting polypeptide (OATP) 1B1 mediates the hepatic uptake of many
drugs including lipid-lowering statins. Decreased OATP1B1 transport activity is often …

Randomized experiments, as developed by Esther Duflo and Abhijit Banerjee at the Abdul
Latif Jameel Poverty Action Lab (J-PAL), offer a novel, evidence-based approach to fighting …

Background Statins are commonly prescribed for cardiovascular diseases which have been
reported to share many contributory underlying mechanisms with erectile dysfunction (ED) …

The current study aimed at the evaluation of, in vivo, the effect of omeprazole on the
pharmacokinetics of rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) …

Purpose Rosuvastatin, a hydroxy methylglutaryl coenzyme A reductase inhibitor;
telmisartan, an angiotensin receptor blocker; and amlodipine, a calcium channel inhibitor …

Linear regression models utilizing a single time point (C max) has been reported for
pravastatin and simvastatin. A new model was developed for the prediction of AUC of statins …

The development of combined drugs, including antihypertensive and hypolipidemic
components, represents the important stage in the clinical pharmacology funds for the …

Создание комбинированных препаратов, включающих антигипертензивные и
гиполипидемические средства, представляет собой важный этап в клинической …