The emerging landscape of salivary diagnostics
Saliva contains a variety of biomolecules, including DNA, coding and noncoding RNA,
proteins, metabolites and microbiota. The changes in the salivary levels of these molecular …
proteins, metabolites and microbiota. The changes in the salivary levels of these molecular …
Salivary biomarkers in oral squamous cell carcinoma–An insight
T Radhika, N Jeddy, S Nithya… - Journal of oral biology …, 2016 - Elsevier
Oral cancer refers to the malignancies that occur in the oral cavity, lip and pharynx with 90%
of oral cancers being squamous cell carcinomas (OSCC). OSCC has the highest mortality …
of oral cancers being squamous cell carcinomas (OSCC). OSCC has the highest mortality …
[HTML][HTML] Salivary and serum interleukin-6 levels in oral premalignant disorders and squamous cell carcinoma: diagnostic value and clinicopathologic correlations
T Dineshkumar, BK Ashwini… - Asian Pacific journal …, 2016 - ncbi.nlm.nih.gov
Aim: To assess the diagnostic utility of serum and salivary interleukin 6 (IL-6) levels in the
differential diagnosis of potentially malignant lesions and conditions (PMLs/PMCs) and oral …
differential diagnosis of potentially malignant lesions and conditions (PMLs/PMCs) and oral …
Salivary 8-hydroxy-2-deoxyguanosine, malondialdehyde, vitamin C, and vitamin E in oral pre-cancer and cancer: diagnostic value and free radical mechanism of …
J Kaur, C Politis, R Jacobs - Clinical oral investigations, 2016 - Springer
Objectives The objectives of this study are to analyze oxidative DNA and lipid damage using
salivary 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), and vitamins C …
salivary 8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), and vitamins C …
Electrochemical bioplatforms for the simultaneous determination of interleukin (IL)-8 mRNA and IL-8 protein oral cancer biomarkers in raw saliva
RM Torrente-Rodríguez, S Campuzano… - Biosensors and …, 2016 - Elsevier
The development of electrochemical magnetobiosensors for the simultaneous determination
of two biomarkers associated with salivary oral cancer, protein IL-8 and its messenger RNA …
of two biomarkers associated with salivary oral cancer, protein IL-8 and its messenger RNA …
[HTML][HTML] IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway
LP Chan, LF Wang, FY Chiang, KW Lee, PL Kuo… - Oncotarget, 2016 - ncbi.nlm.nih.gov
NOD1 (nucleotide-binding oligomerization domain 1) is overexpressed in head and neck
squamous cell carcinoma (HNSCC) cells, as is IL-8 in cancer cells. However, the …
squamous cell carcinoma (HNSCC) cells, as is IL-8 in cancer cells. However, the …
Salivary cytokine levels and oral mucositis in head and neck cancer patients treated with chemotherapy and radiation therapy
P Bossi, C Bergamini, R Miceli, A Cova… - International Journal of …, 2016 - Elsevier
Purpose We assessed the presence of salivary cytokines, their modulation during
chemoradiation therapy (CTRT), and their association with oral mucositis severity in patients …
chemoradiation therapy (CTRT), and their association with oral mucositis severity in patients …
[HTML][HTML] IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma
HY Peng, SS Jiang, JR Hsiao, M Hsiao, YM Hsu… - Molecular …, 2016 - Elsevier
Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the
Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway …
Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway …
Oral biofluid biomarker research: current status and emerging frontiers
Salivary diagnostics is a rapidly advancing field that offers clinicians and patients the
potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete …
potential of rapid, noninvasive diagnostics with excellent accuracy. In order for the complete …
[HTML][HTML] Updated overview of current biomarkers in head and neck carcinoma
K Dahiya, R Dhankhar - World journal of methodology, 2016 - ncbi.nlm.nih.gov
Squamous cell cancer is the most common type of malignancy arising from the epithelial
cells of the head and neck region. Head and neck squamous cell carcinoma (HNSCC) is …
cells of the head and neck region. Head and neck squamous cell carcinoma (HNSCC) is …