Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …

Epigenetic changes are caused by biochemical regulators of gene expression that can be
transferred across generations or through cell division. Epigenetic modifications can arise …

Identification of subjects with a high risk of developing type 2 diabetes (T2D) is fundamental
for prevention of the disease. Consequently, it is essential to search for new biomarkers that …

Importance Epigenetic modifications of the genome, such as DNA methylation and histone
modifications, have been reported to play a role in neurodegenerative diseases (ND) such …

Telomeres are tandem repeat DNA sequences located at distal ends of chromosomes that
protect against genomic DNA degradation and chromosomal instability. Excessive telomere …

Background Children exposed to gestational diabetes mellitus (GDM) are at a higher risk of
developing obesity and type 2 diabetes. This susceptibility might involve brown adipose …

Many epigenetic association studies have attempted to identify DNA methylation markers in
blood that are able to mirror those in target tissues. Although some have suggested potential …

Background: Little is known about epigenetic alterations associated with subcutaneous
adipose tissue (SAT) in obesity. Our aim was to study genome-wide DNA methylation and …

Background New evidence suggests the potential involvement of epigenetic mechanisms in
type 2 diabetes (T2D) as a crucial interface between the effects of genetic predisposition and …

Normal skeletal muscle metabolism is essential for whole body metabolic homoeostasis and
disruptions in muscle metabolism are associated with a number of chronic diseases …